Mohammad Bohlooly-Y

AstraZeneca R&D
Moelndal, O, Sweden

Last Updated: 09/26/2026

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Found 50 publications

Optimised genome editing for precise DNA insertion and substitution using prime editors in zebrafish.

Optimised genome editing for precise DNA insertion and substitution using prime editors in zebrafish.

Journal: eLife
Published: July 07, 2026

Integrative analysis of left ventricle and epicardial adipose tissue identifies SDHA and OGDH as candidate targets for ischemic heart disease.

Integrative analysis of left ventricle and epicardial adipose tissue identifies SDHA and OGDH as candidate targets for ischemic heart disease.

Journal: iScience
Published: October 20, 2025

Altered circadian pattern of activity in a chronic activity-based anorexia nervosa-like female mouse model deficient for GHSR.

Altered circadian pattern of activity in a chronic activity-based anorexia nervosa-like female mouse model deficient for GHSR.

Journal: Psychoneuroendocrinology
Published: September 25, 2024

Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics.

Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics.

Journal: Molecular aspects of medicine
Published: October 30, 2023

Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.

Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.

Journal: Nature communications
Published: September 01, 2023

Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing.

Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing.

Journal: Nature communications
Published: January 26, 2023

Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes.

Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes.

Journal: Science advances
Published: November 16, 2022

A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.

A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.

Journal: Nature communications
Published: October 03, 2022

Selecting the right therapeutic target for kidney disease.

Selecting the right therapeutic target for kidney disease.

Journal: Frontiers in pharmacology
Published: June 16, 2022

Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.

Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.

Journal: Diabetes
Published: March 28, 2022

TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis.

TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis.

Journal: Nature communications
Published: January 05, 2022

A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation.

A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation.

Journal: Frontiers in pharmacology
Published: December 02, 2021
Showing 1-12 of 50

Last Updated: 09/26/2026