Last Updated: 09/26/2026
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Found 14 publications
Outcomes of Percutaneous Coronary Intervention in Patients With Inflammatory Bowel Disease: A Propensity Score-Matched Analysis.
Journal: The Canadian journal of cardiology
Published: August 28, 2025
Preclinical B cell depletion and safety profile of a brain-shuttled crystallizable fragment-silenced CD20 antibody.
Journal: Clinical and translational medicine
Published: July 29, 2024
Addressing Today's Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier Risdiplam.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: June 03, 2021
In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK).
Journal: Investigational new drugs
Published: April 15, 2021
Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats: Impact on P-gp Screening and Compound Optimization.
Journal: The Journal of pharmacology and experimental therapeutics
Published: June 08, 2020
Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: May 29, 2020
Entrectinib, a TRK/ROS1 inhibitor with anti-CNS tumor activity: differentiation from other inhibitors in its class due to weak interaction with P-glycoprotein.
Journal: Neuro-oncology
Published: May 09, 2020
Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.
Journal: Clinical pharmacology and therapeutics
Published: June 14, 2019
Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies.
Journal: The AAPS journal
Published: December 21, 2018
Simultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus Inhibitor.
Journal: The Journal of pharmacology and experimental therapeutics
Published: October 16, 2017
Response to "Breast cancer resistance protein substrate and inhibition evaluation: why, when, and how?".
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: November 02, 2014
Last Updated: 09/26/2026