Mohsen Hosseini

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 26 publications

Extracellular vesicles from aged individuals trigger mitochondrial dysfunction in hematopoietic progenitor cells.

Extracellular vesicles from aged individuals trigger mitochondrial dysfunction in hematopoietic progenitor cells.

Journal: Haematologica

Published: August 05, 2025

Single-cell proteogenomic analysis of clonal evolution in PDX models of AML treated with IDH inhibitors.

Single-cell proteogenomic analysis of clonal evolution in PDX models of AML treated with IDH inhibitors.

Journal: Blood neoplasia

Published: July 28, 2025

Novel and emerging therapeutic strategies for clonal hematopoiesis.

Novel and emerging therapeutic strategies for clonal hematopoiesis.

Journal: Haematologica

Published: July 11, 2025

Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis.

Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis.

Journal: Nature communications

Published: January 13, 2025

TET2 deficiency increases the competitive advantage of hematopoietic stem and progenitor cells through upregulation of thrombopoietin receptor signaling.

TET2 deficiency increases the competitive advantage of hematopoietic stem and progenitor cells through upregulation of thrombopoietin receptor signaling.

Journal: Nature communications

Published: March 22, 2024

Metformin reduces the clonal fitness of Dnmt3a R878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state.

Metformin reduces the clonal fitness of Dnmt3a R878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state.

Journal: Research square

Published: February 26, 2024

Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs.

Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs.

Journal: Nature

Published: January 18, 2024

Targeting STAT5 Signaling Overcomes Resistance to IDH Inhibitors in Acute Myeloid Leukemia through Suppression of Stemness.

Targeting STAT5 Signaling Overcomes Resistance to IDH Inhibitors in Acute Myeloid Leukemia through Suppression of Stemness.

Journal: Cancer research

Published: April 19, 2022

Coordinating Effect of VEGFC and Oleic Acid Participates to Tumor Lymphangiogenesis.

Coordinating Effect of VEGFC and Oleic Acid Participates to Tumor Lymphangiogenesis.

Journal: Cancers

Published: April 07, 2021

Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target.

Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target.

Journal: Blood cancer discovery

Published: December 03, 2020

Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis.

Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis.

Journal: Cell stem cell

Published: September 28, 2020

Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.

Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.

Journal: The Journal of experimental medicine

Published: May 07, 2020

Showing 1-12 of 26

Last Updated: 09/26/2026