Motohiro Okada

Tsu, Japan

Last Updated: 09/26/2026

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Found 118 publications

Development of glutamatergic antipsychotics requires efficient synaptic glutamatergic transmission while preventing NMDA receptor down-regulation and overactivation of extrasynaptic transmission.

Development of glutamatergic antipsychotics requires efficient synaptic glutamatergic transmission while preventing NMDA receptor down-regulation and overactivation of extrasynaptic transmission.

Journal: British journal of pharmacology

Published: April 29, 2026

Risk of Long-Term Clozapine Medication over Decades for Cardiac Adverse Events Including Heart Failure and Its Pathophysiology: A Japan and China Retrospective Cohort Analysis.

Risk of Long-Term Clozapine Medication over Decades for Cardiac Adverse Events Including Heart Failure and Its Pathophysiology: A Japan and China Retrospective Cohort Analysis.

Journal: Medical sciences (Basel, Switzerland)

Published: April 26, 2026

Combined Inhibition of TRPM4/NMDA Receptor Complex and Extrasynaptic NMDA Receptors Is Candidate Therapeutic Target for Suppression of Epileptic Seizures and Improvement of Cognitive Impairments.

Combined Inhibition of TRPM4/NMDA Receptor Complex and Extrasynaptic NMDA Receptors Is Candidate Therapeutic Target for Suppression of Epileptic Seizures and Improvement of Cognitive Impairments.

Journal: Pharmacology research & perspectives

Published: February 17, 2026

Case Report: Successful rechallenge with clozapine after clozapine‑induced cardiomyopathy in a patient with treatment‑resistant schizophrenia.

Case Report: Successful rechallenge with clozapine after clozapine‑induced cardiomyopathy in a patient with treatment‑resistant schizophrenia.

Journal: Asian journal of psychiatry

Published: January 29, 2026

Temporal Dynamics of Auditory Evoked Neural Oscillations Under a Paired-Pulse Suppression Paradigm.

Temporal Dynamics of Auditory Evoked Neural Oscillations Under a Paired-Pulse Suppression Paradigm.

Journal: Brain sciences

Published: January 25, 2026

Paired Pulse Suppression and Prepulse Inhibition in Patients with Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder.

Paired Pulse Suppression and Prepulse Inhibition in Patients with Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder.

Journal: Brain sciences

Published: August 28, 2025

Emerging Role of Tripartite Synaptic Transmission in the Pathomechanism of Autosomal-Dominant Sleep-Related Hypermotor Epilepsy.

Emerging Role of Tripartite Synaptic Transmission in the Pathomechanism of Autosomal-Dominant Sleep-Related Hypermotor Epilepsy.

Journal: International journal of molecular sciences

Published: August 28, 2025

Suicides Mortality of Unemployed Individuals Becomes a Serious Public Health Concern in Japan in Post-COVID-19 Pandemic Era.

Suicides Mortality of Unemployed Individuals Becomes a Serious Public Health Concern in Japan in Post-COVID-19 Pandemic Era.

Journal: International journal of environmental research and public health

Published: July 19, 2025

Exploring effects of chronic d-cycloserine administration on expression of GluN2 subunits and tripartite synaptic transmission in thalamocortical pathway.

Exploring effects of chronic d-cycloserine administration on expression of GluN2 subunits and tripartite synaptic transmission in thalamocortical pathway.

Journal: British journal of pharmacology

Published: July 14, 2025

Subcortical Circuits Among Pedunculopontine Nucleus, Thalamus and Basal Ganglia Play Important Roles in Paroxysmal Arousal in Genetic Rat Models of Autosomal Dominant Sleep-Related Hypermotor Epilepsy.

Subcortical Circuits Among Pedunculopontine Nucleus, Thalamus and Basal Ganglia Play Important Roles in Paroxysmal Arousal in Genetic Rat Models of Autosomal Dominant Sleep-Related Hypermotor Epilepsy.

Journal: International journal of molecular sciences

Published: April 28, 2025

Exploring the pathophysiology underlying clozapine-induced enhancement of glutamatergic transmission through L-glutamate and D-serine release associated with pannexin1 hemichannels.

Exploring the pathophysiology underlying clozapine-induced enhancement of glutamatergic transmission through L-glutamate and D-serine release associated with pannexin1 hemichannels.

Journal: British journal of pharmacology

Published: January 08, 2025

Distinguished Frontal White Matter Abnormalities Between Psychotic and Nonpsychotic Bipolar Disorders in a Pilot Study.

Distinguished Frontal White Matter Abnormalities Between Psychotic and Nonpsychotic Bipolar Disorders in a Pilot Study.

Journal: Brain sciences

Published: December 22, 2024

Showing 1-12 of 118

Last Updated: 09/26/2026