Motomi Konishi - Publications

A synthetic nonapeptide, JAL-TA9, inhibits neuronal cytotoxicity caused by Aβ25-35 aggregation with proteolytic activity.

Journal: Neurobiology of aging

Published: December 12, 2024

Efficient nose-to-brain delivery of nine residues peptide (JAL-TA9) exhibiting hydrolytic activity against amyloid-β.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: October 17, 2024

An 11-mer Synthetic Peptide Suppressing Aggregation of Aβ25-35 and Resolving Its Aggregated Form Improves Test Performance in an Aβ25-35-Induced Alzheimer's Mouse Model.

Journal: Biomolecules

Published: August 03, 2024

SKGQA, a Peptide Derived from the ANA/BTG3 Protein, Cleaves Amyloid-β with Proteolytic Activity.

Journal: Biomolecules

Published: March 14, 2024

Five-mer peptides prevent short-term spatial memory deficits in Aβ25-35-induced Alzheimer's model mouse by suppressing Aβ25-35 aggregation and resolving its aggregate form.

Journal: Alzheimer's research & therapy

Published: November 09, 2022

Structure-Activity Relationship of 5-mer Catalytides, GSGYR and RYGSG.

Journal: Biomolecules

Published: October 17, 2022

Direct Delivery of ANA-TA9, a Peptide Capable of Aβ Hydrolysis, to the Brain by Intranasal Administration.

Journal: Pharmaceutics

Published: August 25, 2021

Amyloid beta cleavage by ANA-TA9, a synthetic peptide from the ANA/BTG3 Box A region.

Journal: Alzheimer's & dementia (New York, N. Y.)

Published: August 19, 2020

Catalytides derived from the Box A region in the ANA/BTG3 protein cleave amyloid-β fragment peptide.

Journal: Heliyon

Published: June 11, 2019

Effects of Cu2+ on conformational change and aggregation of hPrP180-192 with a V180I mutation of the prion protein.

Journal: Biochemical and biophysical research communications

Published: April 24, 2019

The discovery of shorter synthetic proteolytic peptides derived from Tob1 protein.

Journal: Peptides

Published: October 25, 2018

MMP-7 cleaves amyloid β fragment peptides and copper ion inhibits the degradation.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

Published: May 02, 2017