Muhammad A. Farooq

Dongguan, 523000, China

Last Updated: 09/26/2026

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Found 28 publications

The dysregulated unfolded protein response in diabetic kidney disease: mechanisms and crosstalk with cell death pathways.

The dysregulated unfolded protein response in diabetic kidney disease: mechanisms and crosstalk with cell death pathways.

Journal: Frontiers in pharmacology

Published: May 08, 2026

Advanced strategies to enhance the safety, persistence, and efficacy of CAR-T cells in solid tumors.

Advanced strategies to enhance the safety, persistence, and efficacy of CAR-T cells in solid tumors.

Journal: Frontiers in immunology

Published: February 19, 2026

KLRG1 silencing increases the efficacy of CAR NK cell therapy against colon cancer via SHP-2/ZAP-70/NF-κB signal pathway.

KLRG1 silencing increases the efficacy of CAR NK cell therapy against colon cancer via SHP-2/ZAP-70/NF-κB signal pathway.

Journal: Journal of translational medicine

Published: January 07, 2026

Overexpression of HIF-1α via small activating RNA enhances CAR-T cell function in hypoxic microenvironments.

Overexpression of HIF-1α via small activating RNA enhances CAR-T cell function in hypoxic microenvironments.

Journal: Pharmacological research

Published: January 03, 2026

TIPE2 knockdown enhances the anti-tumor efficacy of NKG2D CAR-T cells against pancreatic cancer via activating NF-κb signaling pathway.

TIPE2 knockdown enhances the anti-tumor efficacy of NKG2D CAR-T cells against pancreatic cancer via activating NF-κb signaling pathway.

Journal: Journal of translational medicine

Published: November 11, 2025

GPR132 regulates the function of NK cells through the Gαs/CSK/ZAP70/NF-κB signaling pathway as a potential immune checkpoint.

GPR132 regulates the function of NK cells through the Gαs/CSK/ZAP70/NF-κB signaling pathway as a potential immune checkpoint.

Journal: Science advances

Published: March 05, 2025

Microneedle-based sustained release delivery of TNF-α/IL-6R dual-specific fenobody alleviates inflammation and promotes bone regeneration in rheumatoid arthritis rat model.

Microneedle-based sustained release delivery of TNF-α/IL-6R dual-specific fenobody alleviates inflammation and promotes bone regeneration in rheumatoid arthritis rat model.

Journal: Materials today. Bio

Published: January 31, 2025

The challenges and progress of CAR-T cell therapy in the treatment of solid tumors.

The challenges and progress of CAR-T cell therapy in the treatment of solid tumors.

Journal: Molecular and cellular biochemistry

Published: December 11, 2024

Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer.

Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer.

Journal: Pharmacological research

Published: October 28, 2024

TCR-T cell therapy for solid tumors: challenges and emerging solutions.

TCR-T cell therapy for solid tumors: challenges and emerging solutions.

Journal: Frontiers in pharmacology

Published: September 09, 2024

GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway.

GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: July 25, 2024

A novel strategy of co-expressing CXCR5 and IL-7 enhances CAR-T cell effectiveness in osteosarcoma.

A novel strategy of co-expressing CXCR5 and IL-7 enhances CAR-T cell effectiveness in osteosarcoma.

Journal: Frontiers in immunology

Published: July 17, 2024

Showing 1-12 of 28

Last Updated: 09/26/2026