Muhammad Fakhar

Islamabad, IS, Pakistan

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 8 publications

SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework.

SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework.

Journal: PloS one
Published: April 25, 2022

Structural basis of Klotho binding to VEGFR2 and TRPC1 and repurposing calcium channel blockers as TRPC1 antagonists for the treatment of age-related cardiac hypertrophy.

Structural basis of Klotho binding to VEGFR2 and TRPC1 and repurposing calcium channel blockers as TRPC1 antagonists for the treatment of age-related cardiac hypertrophy.

Journal: Archives of biochemistry and biophysics
Published: March 23, 2021

Molecular dynamics and structural analysis of the binding of COP1 E3 ubiquitin ligase to β-catenin and TRIB pseudokinases.

Molecular dynamics and structural analysis of the binding of COP1 E3 ubiquitin ligase to β-catenin and TRIB pseudokinases.

Journal: Proteins
Published: March 17, 2021

Evidence for NAD+-dependent histone dynamics and tunneling associated conformational transitions in circadian deacetylase SIRT1.

Evidence for NAD+-dependent histone dynamics and tunneling associated conformational transitions in circadian deacetylase SIRT1.

Journal: Journal of molecular graphics & modelling
Published: March 08, 2020

Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors.

Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors.

Journal: PloS one
Published: June 17, 2019

Antagonistic role of Klotho-derived peptides dynamics in the pancreatic cancer treatment through obstructing WNT-1 and Frizzled binding.

Antagonistic role of Klotho-derived peptides dynamics in the pancreatic cancer treatment through obstructing WNT-1 and Frizzled binding.

Journal: Biophysical chemistry
Published: April 22, 2018

Interactive structural analysis of βTrCP1 and PER2 phosphoswitch binding through dynamics simulation assay.

Interactive structural analysis of βTrCP1 and PER2 phosphoswitch binding through dynamics simulation assay.

Journal: Archives of biochemistry and biophysics
Published: March 30, 2018

Targeted inhibition of Klotho binding to fibroblast growth factor 23 prevents hypophosphetemia.

Targeted inhibition of Klotho binding to fibroblast growth factor 23 prevents hypophosphetemia.

Journal: Journal of molecular graphics & modelling
Published: January 15, 2017
Showing 1-8 of 8

Last Updated: 09/26/2026