Mutsuko Niino-Kukimoto

Yokohama, Japan

Last Updated: 09/26/2026

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Found 40 publications

Structural basis for auto-inhibition of the Rac1/Cdc42 guanine nucleotide exchange factor DOCK6 by oligomer formation.

Structural basis for auto-inhibition of the Rac1/Cdc42 guanine nucleotide exchange factor DOCK6 by oligomer formation.

Journal: Communications biology

Published: August 12, 2025

Conformational alteration of DOCK5•ELMO1 signalosome on lipid membrane.

Conformational alteration of DOCK5•ELMO1 signalosome on lipid membrane.

Journal: Communications biology

Published: May 16, 2025

Autism spectrum disorder-associated Sema5A p.Arg676Cys drives Arf6/FE65 signaling and aberrant cell morphogenesis.

Autism spectrum disorder-associated Sema5A p.Arg676Cys drives Arf6/FE65 signaling and aberrant cell morphogenesis.

Journal: Scientific reports

Published: April 20, 2025

EVA1-antibody drug conjugate is a new therapeutic strategy for eliminating glioblastoma-initiating cells.

EVA1-antibody drug conjugate is a new therapeutic strategy for eliminating glioblastoma-initiating cells.

Journal: Neuro-oncology

Published: October 29, 2024

Autism Spectrum Disorder- and/or Intellectual Disability-Associated Semaphorin-5A Exploits the Mechanism by Which Dock5 Signalosome Molecules Control Cell Shape.

Autism Spectrum Disorder- and/or Intellectual Disability-Associated Semaphorin-5A Exploits the Mechanism by Which Dock5 Signalosome Molecules Control Cell Shape.

Journal: Current issues in molecular biology

Published: February 12, 2024

RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.

RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.

Journal: The Journal of biological chemistry

Published: December 28, 2023

A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer.

A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer.

Journal: NPJ precision oncology

Published: November 06, 2023

RhoG-Binding Domain of Elmo1 Ameliorates Excessive Process Elongation Induced by Autism Spectrum Disorder-Associated Sema5A.

RhoG-Binding Domain of Elmo1 Ameliorates Excessive Process Elongation Induced by Autism Spectrum Disorder-Associated Sema5A.

Journal: Pathophysiology : the official journal of the International Society for Pathophysiology

Published: October 10, 2023

A small molecule iCDM-34 identified by in silico screening suppresses HBV DNA through activation of aryl hydrocarbon receptor.

A small molecule iCDM-34 identified by in silico screening suppresses HBV DNA through activation of aryl hydrocarbon receptor.

Journal: Cell death discovery

Published: June 03, 2023

Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor.

Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor.

Journal: Biochemical and biophysical research communications

Published: February 07, 2023

Structural Insight into TNIK Inhibition.

Structural Insight into TNIK Inhibition.

Journal: International journal of molecular sciences

Published: October 04, 2022

Targeting Ras-binding domain of ELMO1 by computational nanobody design.

Targeting Ras-binding domain of ELMO1 by computational nanobody design.

Journal: Communications biology

Published: August 05, 2022

Showing 1-12 of 40

Last Updated: 09/26/2026