Myung-shik S. Lee

Cheonan, Republic of Korea

Last Updated: 09/26/2026

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Found 125 publications

Microglia TFEB activation attenuates Alzheimer's disease pathology by enhancing autophagy-lysosomal function.

Microglia TFEB activation attenuates Alzheimer's disease pathology by enhancing autophagy-lysosomal function.

Journal: Journal of neuroinflammation

Published: October 10, 2025

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.

Journal: medRxiv : the preprint server for health sciences

Published: August 08, 2025

Targeted autophagic clearance of Tau protects against Alzheimer's disease through amelioration of Tau-mediated lysosomal stress.

Targeted autophagic clearance of Tau protects against Alzheimer's disease through amelioration of Tau-mediated lysosomal stress.

Journal: Theranostics

Published: May 28, 2025

Palmitate impairs autophagic degradation via oxidative stress/perilysosomal Ca2+ overload/mTORC1 activation pathway in pancreatic β cells.

Palmitate impairs autophagic degradation via oxidative stress/perilysosomal Ca2+ overload/mTORC1 activation pathway in pancreatic β cells.

Journal: JCI insight

Published: February 25, 2025

GDF15 regulates development and growth of sympathetic neurons to enhance energy expenditure and thermogenesis.

GDF15 regulates development and growth of sympathetic neurons to enhance energy expenditure and thermogenesis.

Journal: Experimental & molecular medicine

Published: October 04, 2024

Regulatory Mechanisms and Therapeutic Implications of Lysosomal Dysfunction in Alzheimer's Disease.

Regulatory Mechanisms and Therapeutic Implications of Lysosomal Dysfunction in Alzheimer's Disease.

Journal: International journal of biological sciences

Published: August 30, 2024

ER-to-lysosome Ca2+ refilling followed by K+ efflux-coupled store-operated Ca2+ entry in inflammasome activation and metabolic inflammation.

ER-to-lysosome Ca2+ refilling followed by K+ efflux-coupled store-operated Ca2+ entry in inflammasome activation and metabolic inflammation.

Journal: eLife

Published: July 02, 2024

DA-1241, a GPR119 Agonist, Ameliorates Fatty Liver Through the Upregulation of TFEB-Mediated Autophagy.

DA-1241, a GPR119 Agonist, Ameliorates Fatty Liver Through the Upregulation of TFEB-Mediated Autophagy.

Journal: Diabetes

Published: May 02, 2024

Autophagy and lysosomal dysfunction in diabetes and its complications.

Autophagy and lysosomal dysfunction in diabetes and its complications.

Journal: Trends in endocrinology and metabolism: TEM

Published: March 26, 2024

ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.

ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.

Journal: Autophagy

Published: January 30, 2024

Role of β-cell autophagy in β-cell physiology and the development of diabetes.

Role of β-cell autophagy in β-cell physiology and the development of diabetes.

Journal: Journal of diabetes investigation

Published: December 15, 2023

A novel NLRP3 inhibitor as a therapeutic agent against monosodium urate-induced gout.

A novel NLRP3 inhibitor as a therapeutic agent against monosodium urate-induced gout.

Journal: Frontiers in immunology

Published: October 05, 2023

Showing 1-12 of 125

Last Updated: 09/26/2026