Nadia De Mota - Publications

Rational design, synthesis and pharmacological characterization of novel aminopeptidase A inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: July 16, 2024

The Metabolically Resistant Apelin-17 Analogue LIT01-196 Reduces Cardiac Dysfunction and Remodelling in Heart Failure After Myocardial Infarction.

Journal: The Canadian journal of cardiology

Published: April 20, 2024

Apelin is altered in subjects with autosomal dominant polycystic kidney disease and preserved kidney function.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Published: November 07, 2022

Apelin and Vasopressin: The Yin and Yang of Water Balance.

Journal: Frontiers in endocrinology

Published: July 02, 2021

QGC606: A Best-in-Class Orally Active Centrally Acting Aminopeptidase A Inhibitor Prodrug for Treating Heart Failure Following Myocardial Infarction.

Journal: The Canadian journal of cardiology

Published: June 24, 2021

LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism.

Journal: Frontiers in pharmacology

Published: May 26, 2021

Effects of firibastat in combination with enalapril and hydrochlorothiazide on blood pressure and vasopressin release in hypertensive DOCA-salt rats.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 03, 2021

Physiological role of the apelin receptor: implication in body fluid homeostasis and hyponatremia

Journal: Biologie aujourd'hui

Published: January 01, 2021

Brain ACE2 activation following brain aminopeptidase A blockade by firibastat in salt-dependent hypertension.

Journal: Clinical science (London, England : 1979)

Published: November 12, 2020

A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia.

Journal: Nature communications

Published: July 15, 2019

A pilot double-blind randomized placebo-controlled crossover pharmacodynamic study of the centrally active aminopeptidase A inhibitor, firibastat, in hypertension.

Journal: Journal of hypertension

Published: March 19, 2019

Plasma Apelin Concentrations in Patients With Polyuria-Polydipsia Syndrome.

Journal: The Journal of clinical endocrinology and metabolism

Published: March 12, 2016