Najet Debili

Villejuif, France

Last Updated: 09/26/2026

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Found 35 publications

Deregulation of the p19/CDK4/CDK6 axis in Jak2V617F megakaryocytes accelerates the development of myelofibrosis.

Deregulation of the p19/CDK4/CDK6 axis in Jak2V617F megakaryocytes accelerates the development of myelofibrosis.

Journal: Leukemia
Published: June 30, 2023

ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis.

ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis.

Journal: Haematologica
Published: September 05, 2022

Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model.

Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model.

Journal: The Journal of clinical investigation
Published: November 01, 2021

Role of Rho-GTPases in megakaryopoiesis.

Role of Rho-GTPases in megakaryopoiesis.

Journal: Small GTPases
Published: February 11, 2021

Dual role of EZH2 in megakaryocyte differentiation.

Dual role of EZH2 in megakaryocyte differentiation.

Journal: Blood
Published: December 19, 2019

Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms.

Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms.

Journal: Oncogene
Published: December 11, 2019

Murine platelet production is suppressed by S1P release in the hematopoietic niche, not facilitated by blood S1P sensing.

Murine platelet production is suppressed by S1P release in the hematopoietic niche, not facilitated by blood S1P sensing.

Journal: Blood advances
Published: January 21, 2019

Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity.

Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity.

Journal: Blood
Published: July 02, 2018

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity.

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity.

Journal: Blood advances
Published: June 04, 2018

Megakaryocyte and polyploidization.

Megakaryocyte and polyploidization.

Journal: Experimental hematology
Published: September 07, 2017

Mutations of the integrin αIIb/β3 intracytoplasmic salt bridge cause macrothrombocytopenia and enlarged platelet α-granules.

Mutations of the integrin αIIb/β3 intracytoplasmic salt bridge cause macrothrombocytopenia and enlarged platelet α-granules.

Journal: American journal of hematology
Published: September 01, 2017

Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect.

Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect.

Journal: Nature communications
Published: July 20, 2016
Showing 1-12 of 35

Last Updated: 09/26/2026