Nancy H. Gudgeon

Birmingham, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 13 publications

Immunometabolic profiling of T cells in response to prolonged moderate intensity cycling in humans.

Immunometabolic profiling of T cells in response to prolonged moderate intensity cycling in humans.

Journal: Exercise immunology review
Published: December 18, 2025

mTOR activity and metabolic reprogramming of CD8+ T cells is impaired under hypoxia and within the multiple myeloma bone marrow.

mTOR activity and metabolic reprogramming of CD8+ T cells is impaired under hypoxia and within the multiple myeloma bone marrow.

Journal: Blood advances
Published: March 10, 2025

Cytoplasmic NAD/H synthesis via NRK1 regulates inflammatory capacity and promotes survival of CD4+ T cells.

Cytoplasmic NAD/H synthesis via NRK1 regulates inflammatory capacity and promotes survival of CD4+ T cells.

Journal: Nature communications
Published: September 23, 2024

IL-7 promotes integrated glucose and amino acid sensing during homeostatic CD4+ T cell proliferation.

IL-7 promotes integrated glucose and amino acid sensing during homeostatic CD4+ T cell proliferation.

Journal: Cell reports
Published: July 29, 2024

Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity.

Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity.

Journal: EMBO molecular medicine
Published: May 17, 2024

TNF-α signals through ITK-Akt-mTOR to drive CD4+ T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis.

TNF-α signals through ITK-Akt-mTOR to drive CD4+ T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis.

Journal: Science signaling
Published: April 23, 2024

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells.

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells.

Journal: Nature communications
Published: January 29, 2024

The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival.

The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival.

Journal: Haematologica
Published: May 03, 2023

Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma.

Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma.

Journal: Blood advances
Published: January 31, 2023

Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.

Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.

Journal: Cell metabolism
Published: August 04, 2022

Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation.

Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation.

Journal: Cell reports
Published: December 06, 2021

1,25-Dihydroxyvitamin D3 suppresses CD4+ T-cell effector functionality by inhibition of glycolysis.

1,25-Dihydroxyvitamin D3 suppresses CD4+ T-cell effector functionality by inhibition of glycolysis.

Journal: Immunology
Published: September 29, 2021
Showing 1-12 of 13

Last Updated: 09/26/2026