Naoki Ishiguro

Birkendorfer Str. 65
Biberach An Der Riss, BW 88397, Germany

Last Updated: 09/26/2026

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Found 607 publications

Microfluidics meets organoids: Kidney and bladder-on-Chip models for preclinical drug delivery assessment.

Microfluidics meets organoids: Kidney and bladder-on-Chip models for preclinical drug delivery assessment.

Journal: Advanced drug delivery reviews

Published: February 27, 2026

Impact of renal hypoxia on OAT1 expression and adefovir-induced cytotoxicity in human 3D-RPTEC spheroids.

Impact of renal hypoxia on OAT1 expression and adefovir-induced cytotoxicity in human 3D-RPTEC spheroids.

Journal: Toxicology and applied pharmacology

Published: December 22, 2025

Impact of renal hypoxia on OAT1 expression and adefovir-induced cytotoxicity in human 3D-RPTEC spheroids.

Impact of renal hypoxia on OAT1 expression and adefovir-induced cytotoxicity in human 3D-RPTEC spheroids.

Journal: Toxicology and applied pharmacology

Published: December 22, 2025

In vitro recapitulation of drug metabolite partitioning into the bile and blood using the icHep system consisting of hepatocytes with an induced open-form bile canaliculus.

In vitro recapitulation of drug metabolite partitioning into the bile and blood using the icHep system consisting of hepatocytes with an induced open-form bile canaliculus.

Journal: Chemico-biological interactions

Published: October 24, 2025

Transporter-transporter interplay determines the renal-predominant elimination of the O-glucuronide metabolite (BI 689875) of vicadrostat in humans.

Transporter-transporter interplay determines the renal-predominant elimination of the O-glucuronide metabolite (BI 689875) of vicadrostat in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: October 20, 2025

Real-world effectiveness, safety and patient-reported outcomes of sarilumab in patients with rheumatoid arthritis: a 52-week, prospective, open-label, non-interventional, observational, nationwide, large-cohort study in Japan (PROFILE-J).

Real-world effectiveness, safety and patient-reported outcomes of sarilumab in patients with rheumatoid arthritis: a 52-week, prospective, open-label, non-interventional, observational, nationwide, large-cohort study in Japan (PROFILE-J).

Journal: RMD open

Published: October 15, 2025

Three-dimensional-cultured renal tubular model reveals FXR-HNF4α-OAT1/3 axis as a target for preventing nucleotide analog-induced kidney injury.

Three-dimensional-cultured renal tubular model reveals FXR-HNF4α-OAT1/3 axis as a target for preventing nucleotide analog-induced kidney injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: September 01, 2025

Enhanced locomotor recovery in mice lacking GlcNAc6ST1 and GlcNAc6ST4 following spinal cord injury.

Enhanced locomotor recovery in mice lacking GlcNAc6ST1 and GlcNAc6ST4 following spinal cord injury.

Journal: Life science alliance

Published: July 26, 2025

A randomized controlled trial comparing romosozumab and denosumab in elderly women with primary osteoporosis and knee osteoarthritis.

A randomized controlled trial comparing romosozumab and denosumab in elderly women with primary osteoporosis and knee osteoarthritis.

Journal: Scientific reports

Published: January 11, 2025

Advanced in vitro evaluation of drug-induced kidney injury using microphysiological systems in drug discovery and development.

Advanced in vitro evaluation of drug-induced kidney injury using microphysiological systems in drug discovery and development.

Journal: Drug metabolism and pharmacokinetics

Published: December 20, 2024

Protocol to develop a proximal tubule-on-chip model based on hiPSC-derived kidney organoids for functional analysis of renal transporters.

Protocol to develop a proximal tubule-on-chip model based on hiPSC-derived kidney organoids for functional analysis of renal transporters.

Journal: STAR protocols

Published: December 02, 2024

Safety and efficacy of filgotinib in Japanese patients with rheumatoid arthritis: Week 156 interim results in FINCH 4.

Safety and efficacy of filgotinib in Japanese patients with rheumatoid arthritis: Week 156 interim results in FINCH 4.

Journal: Modern rheumatology

Published: September 03, 2024

Showing 1-12 of 607

Last Updated: 09/26/2026