Natalie Fuchs

Mainz, RP 55128, Germany

Last Updated: 09/26/2026

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Found 10 publications

HTS-Oracle: Experimentally validated AI-enabled prioritization for generalizable small molecule hit discovery.

HTS-Oracle: Experimentally validated AI-enabled prioritization for generalizable small molecule hit discovery.

Journal: bioRxiv : the preprint server for biology

Published: December 12, 2025

Dual Strategy to Design New Agents Targeting Schistosoma mansoni: Advancing Phenotypic and SmCB1 Inhibitors for Improved Efficacy.

Dual Strategy to Design New Agents Targeting Schistosoma mansoni: Advancing Phenotypic and SmCB1 Inhibitors for Improved Efficacy.

Journal: ACS infectious diseases

Published: April 30, 2024

Structural Modifications of Covalent Cathepsin S Inhibitors: Impact on Affinity, Selectivity, and Permeability.

Structural Modifications of Covalent Cathepsin S Inhibitors: Impact on Affinity, Selectivity, and Permeability.

Journal: ACS medicinal chemistry letters

Published: January 30, 2024

Next Generation of Fluorometric Protease Assays: 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-amides (NBD-Amides) as Class-Spanning Protease Substrates.

Next Generation of Fluorometric Protease Assays: 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-amides (NBD-Amides) as Class-Spanning Protease Substrates.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: June 12, 2023

Subnanomolar Cathepsin S Inhibitors with High Selectivity: Optimizing Covalent Reversible α-Fluorovinylsulfones and α-Sulfonates as Potential Immunomodulators in Cancer.

Subnanomolar Cathepsin S Inhibitors with High Selectivity: Optimizing Covalent Reversible α-Fluorovinylsulfones and α-Sulfonates as Potential Immunomodulators in Cancer.

Journal: ChemMedChem

Published: March 21, 2023

New peptidomimetic rhodesain inhibitors with improved selectivity towards human cathepsins.

New peptidomimetic rhodesain inhibitors with improved selectivity towards human cathepsins.

Journal: European journal of medicinal chemistry

Published: April 06, 2022

Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.

Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.

Journal: ACS chemical biology

Published: March 09, 2022

Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies.

Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies.

Journal: Journal of medicinal chemistry

Published: August 11, 2021

Applicability of a single-use bioreactor compared to a glass bioreactor for the fermentation of filamentous fungi and evaluation of the reproducibility of growth in pellet form.

Applicability of a single-use bioreactor compared to a glass bioreactor for the fermentation of filamentous fungi and evaluation of the reproducibility of growth in pellet form.

Journal: Engineering in life sciences

Published: September 04, 2020

Novel Opportunities for Cathepsin S Inhibitors in Cancer Immunotherapy by Nanocarrier-Mediated Delivery.

Novel Opportunities for Cathepsin S Inhibitors in Cancer Immunotherapy by Nanocarrier-Mediated Delivery.

Journal: Cells

Published: August 11, 2020

Showing 1-10 of 10

Last Updated: 09/26/2026