Natalie J. Jooss

Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 21 publications

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA.

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA.

Journal: Science (New York, N.Y.)

Published: August 14, 2025

comBO: A combined human bone and lympho-myeloid bone marrow organoid for preclinical modeling of hematopoietic disorders.

comBO: A combined human bone and lympho-myeloid bone marrow organoid for preclinical modeling of hematopoietic disorders.

Journal: Cell stem cell

Published: March 03, 2025

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.

Journal: Science translational medicine

Published: October 09, 2024

Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice.

Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice.

Journal: Blood advances

Published: January 19, 2024

Restraining of glycoprotein VI- and integrin α2β1-dependent thrombus formation by platelet PECAM1.

Restraining of glycoprotein VI- and integrin α2β1-dependent thrombus formation by platelet PECAM1.

Journal: Cellular and molecular life sciences : CMLS

Published: July 14, 2023

Generating human bone marrow organoids for disease modeling and drug discovery.

Generating human bone marrow organoids for disease modeling and drug discovery.

Journal: Nature protocols

Published: February 28, 2023

Pharmacological Inhibition of Glycoprotein VI- and Integrin α2β1-Induced Thrombus Formation Modulated by the Collagen Type.

Pharmacological Inhibition of Glycoprotein VI- and Integrin α2β1-Induced Thrombus Formation Modulated by the Collagen Type.

Journal: Thrombosis and haemostasis

Published: February 22, 2023

Platelet glycoprotein VI cluster size is related to thrombus formation and phosphatidylserine exposure in collagen-adherent platelets under arterial shear.

Platelet glycoprotein VI cluster size is related to thrombus formation and phosphatidylserine exposure in collagen-adherent platelets under arterial shear.

Journal: Journal of thrombosis and haemostasis : JTH

Published: October 11, 2022

Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization.

Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization.

Journal: Journal of thrombosis and haemostasis : JTH

Published: August 19, 2022

CLEC-2 Supports Platelet Aggregation in Mouse but not Human Blood at Arterial Shear.

CLEC-2 Supports Platelet Aggregation in Mouse but not Human Blood at Arterial Shear.

Journal: Thrombosis and haemostasis

Published: July 11, 2022

Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear.

Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear.

Journal: International journal of molecular sciences

Published: June 25, 2022

Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling, and thrombus formation.

Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling, and thrombus formation.

Journal: Journal of thrombosis and haemostasis : JTH

Published: April 07, 2022

Showing 1-12 of 21

Last Updated: 09/26/2026