Nathalie Castanon

Bordeaux, France

Last Updated: 09/26/2026

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Found 28 publications

Exploring the neurofunctional potential of saffron bioactives: from mood-related behavioral modulation to brain access of safranal.

Exploring the neurofunctional potential of saffron bioactives: from mood-related behavioral modulation to brain access of safranal.

Journal: Food & function

Published: February 27, 2026

Obesity-induced emotional alterations in mice are associated with impairments of tryptophan metabolism along the kynurenine and indole pathways.

Obesity-induced emotional alterations in mice are associated with impairments of tryptophan metabolism along the kynurenine and indole pathways.

Journal: Brain, behavior, and immunity

Published: May 16, 2025

The immune system: An effective therapeutic target for duloxetine.

The immune system: An effective therapeutic target for duloxetine.

Journal: Brain, behavior, and immunity

Published: April 22, 2025

Effect of saffron extract supplementation on mood in healthy adults with subclinical symptoms of depression: a randomized, double-blind placebo-controlled study.

Effect of saffron extract supplementation on mood in healthy adults with subclinical symptoms of depression: a randomized, double-blind placebo-controlled study.

Journal: The American journal of clinical nutrition

Published: April 07, 2025

Saffron extract interferes with lipopolysaccharide-induced brain activation of the kynurenine pathway and impairment of monoamine neurotransmission in mice.

Saffron extract interferes with lipopolysaccharide-induced brain activation of the kynurenine pathway and impairment of monoamine neurotransmission in mice.

Journal: Frontiers in nutrition

Published: July 28, 2023

Acute Effect of a Saffron Extract (Safr'InsideTM) and Its Main Volatile Compound on the Stress Response in Healthy Young Men: A Randomized, Double Blind, Placebo-Controlled, Crossover Study.

Acute Effect of a Saffron Extract (Safr'InsideTM) and Its Main Volatile Compound on the Stress Response in Healthy Young Men: A Randomized, Double Blind, Placebo-Controlled, Crossover Study.

Journal: Nutrients

Published: May 25, 2023

Tetrahydrobiopterin modulates the behavioral neuroinflammatory response to an LPS challenge in mice.

Tetrahydrobiopterin modulates the behavioral neuroinflammatory response to an LPS challenge in mice.

Journal: Brain, behavior, and immunity

Published: March 22, 2022

Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr'InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders.

Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr'InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders.

Journal: Nutrients

Published: March 14, 2022

Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission.

Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission.

Journal: Pharmaceutics

Published: November 16, 2021

A new experimental design to study inflammation-related versus non-inflammation-related depression in mice.

A new experimental design to study inflammation-related versus non-inflammation-related depression in mice.

Journal: Journal of neuroinflammation

Published: July 22, 2021

Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission.

Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission.

Journal: Nutrients

Published: January 29, 2021

Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry.

Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry.

Journal: Current neuropharmacology

Published: May 26, 2020

Showing 1-12 of 28

Last Updated: 09/26/2026