Nathalie Silvestre

Dr, Transgene SA
Illkirch-graffenstaden, France

Last Updated: 09/26/2026

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Found 20 publications

In memoriam Robert Drillien (1947-2025)

In memoriam Robert Drillien (1947-2025)

Journal: Virologie (Montrouge, France)

Published: March 06, 2026

Therapeutic Poxviruses Induce the Secretion of Immunostimulating and Anti-Tumoral Extracellular Vesicles.

Therapeutic Poxviruses Induce the Secretion of Immunostimulating and Anti-Tumoral Extracellular Vesicles.

Journal: Journal of extracellular vesicles

Published: September 22, 2025

TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironment.

TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironment.

Journal: Journal for immunotherapy of cancer

Published: July 09, 2024

Design and selection of anti-PD-L1 single-domain antibody and tumor necrosis factor superfamily ligands for an optimal vectorization in an oncolytic virus.

Design and selection of anti-PD-L1 single-domain antibody and tumor necrosis factor superfamily ligands for an optimal vectorization in an oncolytic virus.

Journal: Frontiers in bioengineering and biotechnology

Published: June 26, 2023

Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12.

Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12.

Journal: Molecular therapy. Oncology

Published: March 17, 2023

Targeting the tumor mutanome for personalized vaccination in a TMB low non-small cell lung cancer.

Targeting the tumor mutanome for personalized vaccination in a TMB low non-small cell lung cancer.

Journal: Journal for immunotherapy of cancer

Published: March 14, 2022

Viral Delivery of IL-7 Is a Potent Immunotherapy Stimulating Innate and Adaptive Immunity and Confers Survival in Sepsis Models.

Viral Delivery of IL-7 Is a Potent Immunotherapy Stimulating Innate and Adaptive Immunity and Confers Survival in Sepsis Models.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: January 04, 2022

Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject 'cold' tumors.

Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject 'cold' tumors.

Journal: Journal for immunotherapy of cancer

Published: December 27, 2021

Pseudocowpox virus, a novel vector to enhance the therapeutic efficacy of antitumor vaccination.

Pseudocowpox virus, a novel vector to enhance the therapeutic efficacy of antitumor vaccination.

Journal: Clinical & translational immunology

Published: April 21, 2021

Fluorescent Tagged Vaccinia Virus Genome Allows Rapid and Efficient Measurement of Oncolytic Potential and Discovery of Oncolytic Modulators.

Fluorescent Tagged Vaccinia Virus Genome Allows Rapid and Efficient Measurement of Oncolytic Potential and Discovery of Oncolytic Modulators.

Journal: Biomedicines

Published: October 28, 2020

Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques.

Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques.

Journal: NPJ vaccines

Published: December 18, 2019

By Binding CD80 and CD86, the Vaccinia Virus M2 Protein Blocks Their Interactions with both CD28 and CTLA4 and Potentiates CD80 Binding to PD-L1.

By Binding CD80 and CD86, the Vaccinia Virus M2 Protein Blocks Their Interactions with both CD28 and CTLA4 and Potentiates CD80 Binding to PD-L1.

Journal: Journal of virology

Published: February 06, 2019

Showing 1-12 of 20

Last Updated: 09/26/2026