Nathan Mbong

Toronto, ON M5G1L7, Canada

Last Updated: 09/26/2026

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Found 13 publications

KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.

KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.

Journal: Leukemia
Published: September 14, 2022

A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.

A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.

Journal: Leukemia
Published: June 01, 2022

Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.

Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.

Journal: Cell reports
Published: August 09, 2021

Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target.

Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target.

Journal: Blood cancer discovery
Published: December 03, 2020

CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.

CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.

Journal: Blood
Published: August 17, 2020

SIRPαFc treatment targets human acute myeloid leukemia stem cells.

SIRPαFc treatment targets human acute myeloid leukemia stem cells.

Journal: Haematologica
Published: February 13, 2020

Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia.

Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia.

Journal: Cell reports
Published: April 05, 2018

TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding.

TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: July 05, 2016

An Integrated Analysis of Heterogeneous Drug Responses in Acute Myeloid Leukemia That Enables the Discovery of Predictive Biomarkers.

An Integrated Analysis of Heterogeneous Drug Responses in Acute Myeloid Leukemia That Enables the Discovery of Predictive Biomarkers.

Journal: Cancer research
Published: October 01, 2015

AGS67E, an Anti-CD37 Monomethyl Auristatin E Antibody-Drug Conjugate as a Potential Therapeutic for B/T-Cell Malignancies and AML: A New Role for CD37 in AML.

AGS67E, an Anti-CD37 Monomethyl Auristatin E Antibody-Drug Conjugate as a Potential Therapeutic for B/T-Cell Malignancies and AML: A New Role for CD37 in AML.

Journal: Molecular cancer therapeutics
Published: January 27, 2015

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.

Journal: Nature
Published: June 25, 2013

Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion.

Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion.

Journal: Cell stem cell
Published: April 05, 2013
Showing 1-12 of 13

Last Updated: 09/26/2026