Last Updated: 09/26/2026
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Found 19 publications
Loss of the autoimmune risk gene TREX1 reveals a convergence of mechanisms promoting immune tolerance loss and antitumor immunity.
Journal: Science advances
Published: May 06, 2026
CDK10 inhibits innate sensing to constrain antitumor immunity.
Journal: Nature cancer
Published: January 08, 2026
Combined antagonism of Oncostatin M (OSM) and Interleukin 6 (IL-6) provides both anti-fibrotic and anti-inflammatory benefit in pulmonary fibrosis.
Journal: bioRxiv : the preprint server for biology
Published: January 07, 2026
Engineered IL-18 variants with half-life extension and improved stability for cancer immunotherapy.
Journal: Journal for immunotherapy of cancer
Published: June 06, 2025
The IL-22-oncostatin M axis promotes intestinal inflammation and tumorigenesis.
Journal: Nature immunology
Published: June 05, 2024
The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity.
Journal: Cancer immunology research
Published: December 19, 2023
IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control.
Journal: Nature
Published: October 04, 2023
Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer.
Journal: Nature communications
Published: January 31, 2023
CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy.
Journal: Cell reports. Medicine
Published: April 21, 2022
Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.
Journal: Science translational medicine
Published: January 12, 2022
The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: April 02, 2019
Coordination of Immune-Stroma Crosstalk by IL-6 Family Cytokines.
Journal: Frontiers in immunology
Published: February 28, 2019
Last Updated: 09/26/2026