Neel P. Deferm
Overpelt, VLG 3900, Belgium
Last Updated: 09/26/2026
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Found 24 publications
Physiologically Based Pharmacokinetic Modelling of Hydroxyurea in Patients with Sickle Cell Disease: A Special Focus on Lactating Women and Breastfed Infants to Inform Safe Dosing and Breastfeeding Strategies.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: December 15, 2025
A Systematic Review of Published Physiologically Based Pharmacokinetic Models for Drug Excretion Into Human Breastmilk: Knowledge Gaps and Opportunities to Optimize Reporting and Modeling Practices.
Journal: CPT: pharmacometrics & systems pharmacology
Published: November 28, 2025
Predicting Systemic and Liver Bosentan Exposure Using Physiologically-Based Pharmacokinetic Modeling.
Journal: CPT: pharmacometrics & systems pharmacology
Published: April 09, 2025
Postpartum changes in maternal physiology and milk composition: a comprehensive database for developing lactation physiologically-based pharmacokinetic models.
Journal: Frontiers in pharmacology
Published: October 25, 2024
Gastrointestinal Bile Salt Concentrations in Healthy Adults Under Fasted and Fed Conditions: A Systematic Review and Meta-Analysis for Mechanistic Physiologically-Based Pharmacokinetic (PBPK) Modelling.
Journal: The AAPS journal
Published: October 02, 2024
Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK) Modelling-A Contribution from the ConcePTION Project.
Journal: Pharmaceutics
Published: March 17, 2023
Unravelling the Hepatic Elimination Mechanisms of Colistin.
Journal: Pharmaceutical research
Published: October 17, 2022
Case Report: Bosentan and Sildenafil Exposure in Human Milk - A Contribution From the ConcePTION Project.
Journal: Frontiers in pharmacology
Published: February 22, 2022
Bosentan Alters Endo- and Exogenous Bile Salt Disposition in Sandwich-Cultured Human Hepatocytes.
Journal: The Journal of pharmacology and experimental therapeutics
Published: April 25, 2021
Development of a Pig Mammary Epithelial Cell Culture Model as a Non-Clinical Tool for Studying Epithelial Barrier-A Contribution from the IMI-ConcePTION Project.
Journal: Animals : an open access journal from MDPI
Published: April 13, 2021
Glomerular Filtration Rate in Asphyxiated Neonates Under Therapeutic Whole-Body Hypothermia, Quantified by Mannitol Clearance.
Journal: Clinical pharmacokinetics
Published: January 28, 2021
Identification of novel inhibitors of rat Mrp3.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Published: November 11, 2020
Last Updated: 09/26/2026