Neil J. Parrott
Basel, BS 4070, Switzerland
Last Updated: 09/26/2026
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Found 144 publications
Predicting First-in-Human Pharmacokinetics: Comparative Evaluation of Standard PBPK, High-Throughput PBPK, and Machine Learning.
Journal: Molecular pharmaceutics
Published: March 30, 2026
High-Throughput Physiologically Based Pharmacokinetic Model for Rodent Pharmacokinetics Prediction Using Machine Learning-Predicted Inputs and a Large In Vivo Pharmacokinetics Data Set.
Journal: Molecular pharmaceutics
Published: January 30, 2026
PQRI Workshop: Model-Informed Drug Development (MIDD) Approaches in Pediatric Formulation Development.
Journal: The AAPS journal
Published: November 19, 2025
Future directions in drug-drug interaction evaluations: Industry perspective on the ICH M12 guidance.
Journal: Drug metabolism and pharmacokinetics
Published: November 14, 2025
Combining the novel all-human co-cultured hepatocytes system with physiologically based pharmacokinetic modeling to assess the translatability of cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase induction data.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: November 06, 2025
Fraction metabolized by cytochrome P450 enzymes: A comprehensive evaluation of the translatability of an in vitro HepatoPac assay.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: October 24, 2025
Current status of prediction of IL-6 mediated cytochrome P450 activity modulation using in vitro data and PBPK modeling.
Journal: Drug metabolism and pharmacokinetics
Published: September 26, 2025
Optimization of In Vitro CYP3A4 TDI Assay Conditions and Use of Derived Parameters for Clinical DDI Risk Assessment Using Static and Dynamic Models.
Journal: The AAPS journal
Published: June 09, 2025
Physiologically-Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges.
Journal: CPT: pharmacometrics & systems pharmacology
Published: May 30, 2025
Prospective DDI Risk Assessment of Vicasinabin with PBPK Modeling by Integrating In Vitro Data.
Journal: Clinical pharmacology and therapeutics
Published: December 19, 2024
Embracing the future of medicine with virtual patients.
Journal: Drug discovery today
Published: December 09, 2024
Clinical Exploration and Physiologically Based Modelling of the Impact of Hepatic Impairment on Entrectinib Pharmacokinetics.
Journal: Clinical pharmacokinetics
Published: December 04, 2024
Last Updated: 09/26/2026