Neil Maclean

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 33 publications

Intracellular IL-23R is necessary for mitotic spindle formation and viability in AML.

Intracellular IL-23R is necessary for mitotic spindle formation and viability in AML.

Journal: Leukemia
Published: December 10, 2025

Mitochondrial RNA degradation regulates differentiation, stemness, and immune sensitivity in acute myeloid leukemia.

Mitochondrial RNA degradation regulates differentiation, stemness, and immune sensitivity in acute myeloid leukemia.

Journal: Nature communications
Published: May 05, 2025

SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell-Mediated Cytotoxicity.

SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell-Mediated Cytotoxicity.

Journal: Blood cancer discovery
Published: June 06, 2024

IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells.

IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells.

Journal: Leukemia
Published: June 19, 2021

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.

Journal: Nature cell biology
Published: May 11, 2021

Transduction of Primary AML Cells with Lentiviral Vector for In Vitro Study or In Vivo Engraftment.

Transduction of Primary AML Cells with Lentiviral Vector for In Vitro Study or In Vivo Engraftment.

Journal: STAR protocols
Published: December 30, 2020

Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production.

Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production.

Journal: Blood
Published: September 09, 2020

A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity.

A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity.

Journal: JCI insight
Published: June 19, 2020

The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.

The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.

Journal: Science translational medicine
Published: October 12, 2019

The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids.

The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids.

Journal: Cell stem cell
Published: June 08, 2019

Novel L-nucleoside analogue, 5-fluorotroxacitabine, displays potent efficacy against acute myeloid leukemia.

Novel L-nucleoside analogue, 5-fluorotroxacitabine, displays potent efficacy against acute myeloid leukemia.

Journal: Haematologica
Published: May 14, 2019

Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.

Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.

Journal: Cell stem cell
Published: May 03, 2019
Showing 1-12 of 33

Last Updated: 09/26/2026