Neil Q. Mcdonald

Malet Street
London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 63 publications

Discovery of a sulfotyrosine-motif in the human TrkB extracellular domain required for agonist activation.

Discovery of a sulfotyrosine-motif in the human TrkB extracellular domain required for agonist activation.

Journal: bioRxiv : the preprint server for biology

Published: June 04, 2026

A long-chain heparan sulfate capture mechanism directs paracrine GDNF-GFRα1 signalling through RET.

A long-chain heparan sulfate capture mechanism directs paracrine GDNF-GFRα1 signalling through RET.

Journal: bioRxiv : the preprint server for biology

Published: June 04, 2026

RETurn of the Gene. Post scriptum.

RETurn of the Gene. Post scriptum.

Journal: Endocrine-related cancer

Published: April 19, 2026

The chordoid glioma PRKCA D463H mutation is a kinase inactive, gain-of-function allele that induces early-onset chondrosarcoma in mice.

The chordoid glioma PRKCA D463H mutation is a kinase inactive, gain-of-function allele that induces early-onset chondrosarcoma in mice.

Journal: Science signaling

Published: November 04, 2025

RET receptor tyrosine kinase architecture, assemblies, and activation.

RET receptor tyrosine kinase architecture, assemblies, and activation.

Journal: Endocrine-related cancer

Published: August 22, 2025

Penetrant PKCβ mutation in ATLL displays a mixed gain-of-function.

Penetrant PKCβ mutation in ATLL displays a mixed gain-of-function.

Journal: The Biochemical journal

Published: August 12, 2025

Lessons in conformational signalling: non-catalytic functions of protein kinase C isozymes.

Lessons in conformational signalling: non-catalytic functions of protein kinase C isozymes.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Published: April 07, 2025

Structural basis of Fanconi anemia pathway activation by FANCM.

Structural basis of Fanconi anemia pathway activation by FANCM.

Journal: The EMBO journal

Published: March 11, 2025

Kinome profiling reveals pathogenic variant specific protein signalling networks in MEN2 children with Medullary Thyroid Cancer.

Kinome profiling reveals pathogenic variant specific protein signalling networks in MEN2 children with Medullary Thyroid Cancer.

Journal: NPJ precision oncology

Published: November 22, 2024

CARM1/PRMT4 facilitates XPF-ERCC1 heterodimer assembly and maintains nucleotide excision repair activity.

CARM1/PRMT4 facilitates XPF-ERCC1 heterodimer assembly and maintains nucleotide excision repair activity.

Journal: Nucleic acids research

Published: July 26, 2024

Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multisite polarity substrate Lgl.

Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multisite polarity substrate Lgl.

Journal: Nature structural & molecular biology

Published: January 30, 2024

Study of an FBXO7 patient mutation reveals Fbxo7 and PI31 co-regulate proteasomes and mitochondria.

Study of an FBXO7 patient mutation reveals Fbxo7 and PI31 co-regulate proteasomes and mitochondria.

Journal: The FEBS journal

Published: December 06, 2023

Showing 1-12 of 63

Last Updated: 09/26/2026