Nesli-ece Sen

Heinrich Hoffmann Str. 7
Frankfurt Am Main, HE 60528, Germany

Last Updated: 09/26/2026

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Found 15 publications

Astro-Versus Microglia-Enriched Transcriptomes from Aged Atxn2-CAG100-Knockin Mice Suggest Underlying Pathology of RNA Processing at Ribosomes, and Possibly at U-Bodies.

Astro-Versus Microglia-Enriched Transcriptomes from Aged Atxn2-CAG100-Knockin Mice Suggest Underlying Pathology of RNA Processing at Ribosomes, and Possibly at U-Bodies.

Journal: Cells

Published: March 25, 2026

Bioinformatic Analyses of the Ataxin-2 Family Since Algae Emphasize Its Small Isoforms, Large Chimerisms, and the Importance of Human Exon 1B as Target of Therapies to Prevent Neurodegeneration.

Bioinformatic Analyses of the Ataxin-2 Family Since Algae Emphasize Its Small Isoforms, Large Chimerisms, and the Importance of Human Exon 1B as Target of Therapies to Prevent Neurodegeneration.

Journal: International journal of molecular sciences

Published: January 09, 2026

Multiomics approach identifies SERPINB1 as candidate biomarker for spinocerebellar ataxia type 2.

Multiomics approach identifies SERPINB1 as candidate biomarker for spinocerebellar ataxia type 2.

Journal: Scientific reports

Published: May 27, 2025

Spinal Cord Phosphoproteome of SCA2 Mouse Model Reveals Alteration of ATXN2-N-Term PRM-SH3-Actin Interactome and of Autophagy.

Spinal Cord Phosphoproteome of SCA2 Mouse Model Reveals Alteration of ATXN2-N-Term PRM-SH3-Actin Interactome and of Autophagy.

Journal: Molecular & cellular proteomics : MCP

Published: April 21, 2025

Limited proteolysis-coupled mass spectrometry captures proteome-wide protein structural alterations and biomolecular condensation in living cells.

Limited proteolysis-coupled mass spectrometry captures proteome-wide protein structural alterations and biomolecular condensation in living cells.

Journal: Molecular systems biology

Published: April 07, 2025

ATXN2L primarily interacts with NUFIP2, the absence of ATXN2L results in NUFIP2 depletion, and the ATXN2-polyQ expansion triggers NUFIP2 accumulation.

ATXN2L primarily interacts with NUFIP2, the absence of ATXN2L results in NUFIP2 depletion, and the ATXN2-polyQ expansion triggers NUFIP2 accumulation.

Journal: Neurobiology of disease

Published: February 27, 2025

Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates.

Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates.

Journal: Molecular cell

Published: August 23, 2021

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.

Journal: Neurobiology of disease

Published: September 23, 2020

Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength.

Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength.

Journal: International journal of molecular sciences

Published: August 20, 2020

Mid-Gestation lethality of Atxn2l-Ablated Mice.

Mid-Gestation lethality of Atxn2l-Ablated Mice.

Journal: International journal of molecular sciences

Published: June 19, 2020

In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism.

In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism.

Journal: International journal of molecular sciences

Published: November 04, 2019

SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes.

SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes.

Journal: International journal of molecular sciences

Published: May 31, 2019

Showing 1-12 of 15

Last Updated: 09/26/2026