Nesli E. Sen

Istanbul, Turkey

Last Updated: 09/26/2026

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Found 13 publications

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.

Journal: Cell

Published: November 25, 2025

A global genetic interaction map of a human cell reveals conserved principles of genetic networks.

A global genetic interaction map of a human cell reveals conserved principles of genetic networks.

Journal: bioRxiv : the preprint server for biology

Published: July 09, 2025

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.

Journal: Nature

Published: August 25, 2023

TR-FRET-Based Immunoassay to Measure Ataxin-2 as a Target Engagement Marker in Spinocerebellar Ataxia Type 2.

TR-FRET-Based Immunoassay to Measure Ataxin-2 as a Target Engagement Marker in Spinocerebellar Ataxia Type 2.

Journal: Molecular neurobiology

Published: October 11, 2022

The Complex Genetic Landscape of Hereditary Ataxias in Turkey and Implications in Clinical Practice.

The Complex Genetic Landscape of Hereditary Ataxias in Turkey and Implications in Clinical Practice.

Journal: Movement disorders : official journal of the Movement Disorder Society

Published: October 13, 2020

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence.

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence.

Journal: Cells

Published: September 03, 2020

Revisiting the complex architecture of ALS in Turkey: Expanding genotypes, shared phenotypes, molecular networks, and a public variant database.

Revisiting the complex architecture of ALS in Turkey: Expanding genotypes, shared phenotypes, molecular networks, and a public variant database.

Journal: Human mutation

Published: December 12, 2019

Elevated Global DNA Methylation Is Not Exclusive to Amyotrophic Lateral Sclerosis and Is Also Observed in Spinocerebellar Ataxia Types 1 and 2.

Elevated Global DNA Methylation Is Not Exclusive to Amyotrophic Lateral Sclerosis and Is Also Observed in Spinocerebellar Ataxia Types 1 and 2.

Journal: Neuro-degenerative diseases

Published: July 07, 2017

PINK1 and Ataxin-2 as modifiers of growth.

PINK1 and Ataxin-2 as modifiers of growth.

Journal: Oncotarget

Published: April 22, 2017

Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels.

Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels.

Journal: Neurobiology of disease

Published: July 21, 2016

Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations.

Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations.

Journal: Molecular & cellular proteomics : MCP

Published: November 09, 2015

Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.

Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.

Journal: PloS one

Published: November 17, 2014

Showing 1-12 of 13

Last Updated: 09/26/2026