Ngee K. Chua
Parkville, VIC, Australia
Last Updated: 09/26/2026
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Found 22 publications
Efferocytosis of apoptotic bodies drives SARS-CoV-2 infection and macrophage inflammation.
Journal: Nature communications
Published: January 04, 2026
The benchmarking and application of tag-degraders in vivo to validate therapeutic targets.
Journal: Nature communications
Published: June 12, 2025
The E3-ome gene-centric compendium reveals the human E3 ligase landscape.
Journal: Cell
Published: February 16, 2025
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency.
Journal: The EMBO journal
Published: December 17, 2021
Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin.
Journal: Cancer research
Published: November 22, 2021
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms.
Journal: Nature communications
Published: April 22, 2021
The Degron Architecture of Squalene Monooxygenase and How Specific Lipids Calibrate Levels of This Key Cholesterol Synthesis Enzyme.
Journal: Advances in experimental medicine and biology
Published: September 26, 2020
Lipid sensing tips the balance for a key cholesterol synthesis enzyme.
Journal: Journal of lipid research
Published: May 07, 2020
A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 15, 2020
Squalene monooxygenase: a journey to the heart of cholesterol synthesis.
Journal: Progress in lipid research
Published: March 03, 2020
Amiodarone disrupts cholesterol biosynthesis pathway and causes accumulation of circulating desmosterol by inhibiting 24-dehydrocholesterol reductase.
Journal: Journal of internal medicine
Published: February 26, 2020
Last Updated: 09/26/2026