Last Updated: 09/26/2026
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Found 29 publications
Validating a home-based proxy- and self-administered quantitative sensory testing in youth and young adults undergoing regional anesthesia for orthopedic procedures.
Journal: Regional anesthesia and pain medicine
Published: July 17, 2025
Identification of 2-Sulfonyl/Sulfonamide Pyrimidines as Covalent Inhibitors of WRN Using a Multiplexed High-Throughput Screening Assay.
Journal: Biochemistry
Published: July 05, 2023
Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists.
Journal: The Journal of biological chemistry
Published: July 26, 2022
Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast Cancer.
Journal: Molecular cancer therapeutics
Published: April 28, 2021
Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Journal: Nature communications
Published: December 22, 2020
The SF3b Complex is an Integral Component of the Spliceosome and Targeted by Natural Product-Based Inhibitors.
Journal: Sub-cellular biochemistry
Published: November 30, 2020
Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3.
Journal: ACS medicinal chemistry letters
Published: September 25, 2020
Discovery of 2,6-Dimethylpiperazines as Allosteric Inhibitors of CPS1.
Journal: ACS medicinal chemistry letters
Published: March 20, 2020
Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket.
Journal: Cell chemical biology
Published: October 23, 2019
The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity.
Journal: The Journal of biological chemistry
Published: July 09, 2019
Author Correction: Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Journal: Nature communications
Published: June 06, 2019
The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.
Journal: Genes & development
Published: December 20, 2017
Last Updated: 09/26/2026