Nicholas J. Gascoigne

Singapore, Singapore

Last Updated: 09/26/2026

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Found 76 publications

The role of Themis in development of type 2 diabetes.

The role of Themis in development of type 2 diabetes.

Journal: Research square

Published: November 24, 2025

Themis differentially regulates T follicular helper cell differentiation during early and late stages of chronic viral infection.

Themis differentially regulates T follicular helper cell differentiation during early and late stages of chronic viral infection.

Journal: Frontiers in immunology

Published: May 30, 2025

Tuning the sensitivity of mechanosensory receptors through histidine scanning.

Tuning the sensitivity of mechanosensory receptors through histidine scanning.

Journal: Cell

Published: April 04, 2025

Non-viral, high throughput genetic engineering of primary immune cells using nanostraw-mediated transfection.

Non-viral, high throughput genetic engineering of primary immune cells using nanostraw-mediated transfection.

Journal: Biomaterials

Published: November 14, 2024

Protocol for the simultaneous activation and lentiviral transduction of primary human T cells with artificial T cell receptors.

Protocol for the simultaneous activation and lentiviral transduction of primary human T cells with artificial T cell receptors.

Journal: STAR protocols

Published: November 08, 2024

Occlusion of TCR binding to HLA-A*11:01 by a non-pathogenic human alloantibody.

Occlusion of TCR binding to HLA-A*11:01 by a non-pathogenic human alloantibody.

Journal: Cellular and molecular life sciences : CMLS

Published: August 08, 2024

Spatial cartography of human thymus enables the geopositioning of lineage transcription factors in rare mimetic thymic epithelial cells.

Spatial cartography of human thymus enables the geopositioning of lineage transcription factors in rare mimetic thymic epithelial cells.

Journal: Nature communications

Published: June 25, 2024

Antigen-antibody complex density and antibody-induced HLA protein unfolding influence Fc-mediated antibody effector function.

Antigen-antibody complex density and antibody-induced HLA protein unfolding influence Fc-mediated antibody effector function.

Journal: Frontiers in immunology

Published: May 25, 2024

TCR-like antibody and GITR signaling lead to effective CAR-T against solid tumor.

TCR-like antibody and GITR signaling lead to effective CAR-T against solid tumor.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: February 07, 2024

Protocol for structural modeling of antibody to human leukocyte antigen interaction using discovery and targeted cross-linking mass spectrometry.

Protocol for structural modeling of antibody to human leukocyte antigen interaction using discovery and targeted cross-linking mass spectrometry.

Journal: STAR protocols

Published: October 24, 2023

Singapore's diverse immunology landscape: interconnected research networks enabling blue sky ideas through to translation.

Singapore's diverse immunology landscape: interconnected research networks enabling blue sky ideas through to translation.

Journal: Immunology and cell biology

Published: August 07, 2023

SHP-1 Regulates CD8+ T Cell Effector Function but Plays a Subtle Role with SHP-2 in T Cell Exhaustion Due to a Stage-Specific Nonredundant Functional Relay.

SHP-1 Regulates CD8+ T Cell Effector Function but Plays a Subtle Role with SHP-2 in T Cell Exhaustion Due to a Stage-Specific Nonredundant Functional Relay.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: July 10, 2023

Showing 1-12 of 76

Last Updated: 09/26/2026