Nicholas J. Lynch

Cambridge, ENG CB30ES, United Kingdom

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 11 publications

Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections.

Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections.

Journal: Science translational medicine

Published: June 17, 2026

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID.

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID.

Journal: Immunology

Published: April 22, 2025

Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection.

Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection.

Journal: The Journal of infectious diseases

Published: August 07, 2023

Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice.

Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice.

Journal: Frontiers in immunology

Published: March 23, 2023

Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID-19.

Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID-19.

Journal: Clinical and translational medicine

Published: May 22, 2022

Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19.

Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19.

Journal: Frontiers in immunology

Published: December 22, 2021

Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins.

Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins.

Journal: Frontiers in immunology

Published: May 25, 2021

Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role.

Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role.

Journal: Acta neuropathologica communications

Published: July 22, 2020

The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface.

The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface.

Journal: Infection and immunity

Published: October 10, 2018

Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection.

Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 08, 2014

The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.

The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.

Journal: PLoS pathogens

Published: March 08, 2012

Showing 1-11 of 11

Last Updated: 09/26/2026