Nicholas P. Lockyer
Manchester, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 18 publications
Deficient de-S-acylation in aging and CLN1 contributes to lyso-mitochondrial dysfunction, lipid dyshomeostasis, and resultant lipofuscin biogenesis.
Journal: Research square
Published: February 23, 2026
Lipofuscin accumulation in aging and CLN1 is associated with deficient de-S-acylation, lyso-mitochondrial dysfunction, and lipid dyshomeostasis.
Journal: Acta neuropathologica
Published: February 03, 2026
Improvements in high-yield detection and localisation of cholesterol in murine brains using water cluster beam secondary ion mass spectrometry.
Journal: Analytical and bioanalytical chemistry
Published: October 15, 2025
Resolving agrochemical penetration in wheat leaves with secondary ion mass spectrometry imaging and depth profiling.
Journal: Analytical and bioanalytical chemistry
Published: August 06, 2025
Molecular elucidation of brain lipofuscin in aging and Neuronal Ceroid Lipofuscinosis.
Journal: Research square
Published: April 01, 2025
Visualizing active fungicide formulation mobility in tomato leaves with desorption electrospray ionisation mass spectrometry imaging.
Journal: The Analyst
Published: November 22, 2024
Accumulation of Bioactive Lipid Species in LPS-Induced Neuroinflammation Models Analysed with Multi-Modal Mass Spectrometry Imaging.
Journal: International journal of molecular sciences
Published: September 06, 2024
Mass Spectrometry Imaging for Spatial Chemical Profiling of Vegetative Parts of Plants.
Journal: Plants (Basel, Switzerland)
Published: March 30, 2022
Metabolism in action: stable isotope probing using vibrational spectroscopy and SIMS reveals kinetic and metabolic flux of key substrates.
Journal: The Analyst
Published: January 19, 2021
Microdistribution and quantification of the boron neutron capture therapy drug BPA in primary cell cultures of human glioblastoma tumour by NanoSIMS.
Journal: The Analyst
Published: September 19, 2019
The influence of polyatomic primary ion chemistry on matrix effects in secondary ion mass spectrometry analysis.
Journal: Rapid communications in mass spectrometry : RCM
Published: June 19, 2018
Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques.
Journal: Scientific reports
Published: July 07, 2016
Last Updated: 09/26/2026