Nico Zinn

Heidelberg, BW 69117, Germany

Last Updated: 09/26/2026

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Found 24 publications

Discovery of an Orally Available Potent ER Aminopeptidase 1 (ERAP1) Inhibitor That Enhances Antitumor Responses and Limits Inflammatory Autoimmunity In Vivo.

Discovery of an Orally Available Potent ER Aminopeptidase 1 (ERAP1) Inhibitor That Enhances Antitumor Responses and Limits Inflammatory Autoimmunity In Vivo.

Journal: Journal of medicinal chemistry

Published: June 22, 2026

Discovery and optimization of pyrrolopyrimidines as highly potent, selective and brain-penetrant LRRK2 inhibitors.

Discovery and optimization of pyrrolopyrimidines as highly potent, selective and brain-penetrant LRRK2 inhibitors.

Journal: RSC medicinal chemistry

Published: September 24, 2025

Impact of Local Air Pressure on Ion Mobilities and Data Consistency in diaPASEF-Based High Throughput Proteomics.

Impact of Local Air Pressure on Ion Mobilities and Data Consistency in diaPASEF-Based High Throughput Proteomics.

Journal: Journal of proteome research

Published: January 24, 2025

PeptideForest: Semisupervised Machine Learning Integrating Multiple Search Engines for Peptide Identification.

PeptideForest: Semisupervised Machine Learning Integrating Multiple Search Engines for Peptide Identification.

Journal: Journal of proteome research

Published: January 22, 2025

Phenotype-Led Identification of IL-10 Upregulators in Human CD4+ T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 Inhibitors.

Phenotype-Led Identification of IL-10 Upregulators in Human CD4+ T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 Inhibitors.

Journal: Journal of medicinal chemistry

Published: January 09, 2025

mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription.

mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription.

Journal: Molecular cell

Published: June 06, 2023

Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs.

Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs.

Journal: Angewandte Chemie (International ed. in English)

Published: July 12, 2021

Improved Proteomics-Based Drug Mechanism-of-Action Studies Using 16-Plex Isobaric Mass Tags.

Improved Proteomics-Based Drug Mechanism-of-Action Studies Using 16-Plex Isobaric Mass Tags.

Journal: Journal of proteome research

Published: February 23, 2021

Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis.

Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis.

Journal: Nature communications

Published: September 12, 2020

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices.

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices.

Journal: The European respiratory journal

Published: February 03, 2020

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2.

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2.

Journal: Communications biology

Published: November 07, 2019

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor.

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor.

Journal: ACS medicinal chemistry letters

Published: January 23, 2019

Showing 1-12 of 24

Last Updated: 09/26/2026