Nicolaas Salomane

University Of Cape Town, Observatory
Cape Town, WC 7925, South Africa

Last Updated: 09/26/2026

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Found 9 publications

Optimization of 2,8-Diaryl-1,5-naphthyridines as Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy.

Optimization of 2,8-Diaryl-1,5-naphthyridines as Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy.

Journal: Journal of medicinal chemistry

Published: October 07, 2025

Small Molecule Kinase Inhibitors with In Vitro β-Hematin Formation and Plasmodium falciparum Protein Kinase G Inhibitory Activity Identified Using Machine Learning.

Small Molecule Kinase Inhibitors with In Vitro β-Hematin Formation and Plasmodium falciparum Protein Kinase G Inhibitory Activity Identified Using Machine Learning.

Journal: ChemMedChem

Published: September 04, 2025

Targeting Aurora Kinases as Essential Cell-Cycle Regulators to Deliver Multi-Stage Antimalarials Against Plasmodium Falciparum.

Targeting Aurora Kinases as Essential Cell-Cycle Regulators to Deliver Multi-Stage Antimalarials Against Plasmodium Falciparum.

Journal: Angewandte Chemie (International ed. in English)

Published: August 22, 2025

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model.

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model.

Journal: Journal of medicinal chemistry

Published: August 14, 2025

The impact of Iso-mukaadial acetate on Plasmodium falciparum transcriptional gene regulation.

The impact of Iso-mukaadial acetate on Plasmodium falciparum transcriptional gene regulation.

Journal: Scientific reports

Published: June 20, 2025

Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual Plasmodium Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria.

Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual Plasmodium Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria.

Journal: Journal of medicinal chemistry

Published: May 16, 2025

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy.

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy.

Journal: Journal of medicinal chemistry

Published: June 25, 2024

Iso-mukaadial acetate and ursolic acid acetate inhibit the chaperone activity of Plasmodium falciparum heat shock protein 70-1.

Iso-mukaadial acetate and ursolic acid acetate inhibit the chaperone activity of Plasmodium falciparum heat shock protein 70-1.

Journal: Cell stress & chaperones

Published: February 15, 2021

Draft Genome Sequences of Seven Chryseobacterium Type Strains.

Draft Genome Sequences of Seven Chryseobacterium Type Strains.

Journal: Microbiology resource announcements

Published: November 06, 2018

Showing 1-9 of 9

Last Updated: 09/26/2026