Nicolas Gouault

Rennes, 35000, France

Last Updated: 09/26/2026

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Found 19 publications

Synthesis of uniflorol B, a chromanone metabolite of Calea uniflora, and investigation of novel analogues as anti-leishmanial agents.

Synthesis of uniflorol B, a chromanone metabolite of Calea uniflora, and investigation of novel analogues as anti-leishmanial agents.

Journal: Organic & biomolecular chemistry

Published: June 16, 2026

The orphan receptor GPR84 drives inflammation in Buruli ulcer development.

The orphan receptor GPR84 drives inflammation in Buruli ulcer development.

Journal: Science translational medicine

Published: April 15, 2026

Synthesis of 4-hydroxypiperidines containing a quaternary stereocenter by aza-Prins cyclization.

Synthesis of 4-hydroxypiperidines containing a quaternary stereocenter by aza-Prins cyclization.

Journal: Organic & biomolecular chemistry

Published: January 08, 2025

Accessing spiropiperidines from dihydropyridones through tandem triflation-allylation and ring-closing metathesis (RCM).

Accessing spiropiperidines from dihydropyridones through tandem triflation-allylation and ring-closing metathesis (RCM).

Journal: Organic & biomolecular chemistry

Published: June 12, 2023

Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases.

Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases.

Journal: Molecules (Basel, Switzerland)

Published: August 26, 2022

Irreversible inhibitors of the proline racemase unveil innovative mechanism of action as antibacterial agents against Clostridioides difficile.

Irreversible inhibitors of the proline racemase unveil innovative mechanism of action as antibacterial agents against Clostridioides difficile.

Journal: Chemical biology & drug design

Published: September 24, 2021

Structural and molecular bases to IRE1 activity modulation.

Structural and molecular bases to IRE1 activity modulation.

Journal: The Biochemical journal

Published: May 18, 2021

Prodrugs as new therapies against Chagas disease: in vivo synergy between Trypanosoma cruzi proline racemase inhibitors and benznidazole.

Prodrugs as new therapies against Chagas disease: in vivo synergy between Trypanosoma cruzi proline racemase inhibitors and benznidazole.

Journal: Journal of global antimicrobial resistance

Published: April 09, 2021

Lichen butyrolactone derivatives disrupt oral bacterial membrane.

Lichen butyrolactone derivatives disrupt oral bacterial membrane.

Journal: Fitoterapia

Published: June 08, 2019

Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography.

Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography.

Journal: PLoS neglected tropical diseases

Published: May 11, 2018

Isolation and Structure Identification of Novel Brominated Diketopiperazines from Nocardia ignorata-A Lichen-Associated Actinobacterium.

Isolation and Structure Identification of Novel Brominated Diketopiperazines from Nocardia ignorata-A Lichen-Associated Actinobacterium.

Journal: Molecules (Basel, Switzerland)

Published: January 25, 2017

Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase.

Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

Published: October 18, 2016

Showing 1-12 of 19

Last Updated: 09/26/2026