Nicolas P. Pionnier

Pembroke Place
Liverpool, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 26 publications

Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis.

Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis.

Journal: Frontiers in microbiology
Published: November 28, 2023

NKp46+ natural killer cells develop an activated/memory-like phenotype and contribute to innate immunity against experimental filarial infection.

NKp46+ natural killer cells develop an activated/memory-like phenotype and contribute to innate immunity against experimental filarial infection.

Journal: Frontiers in immunology
Published: June 14, 2022

A mouse infection model and long-term lymphatic endothelium co-culture system to evaluate drugs against adult Brugia malayi.

A mouse infection model and long-term lymphatic endothelium co-culture system to evaluate drugs against adult Brugia malayi.

Journal: PLoS neglected tropical diseases
Published: February 01, 2022

Onchocerca ochengi male worms implanted in SCID mice and Gerbil: Relationship between microfilaridermia status of cows, nodular worm viability and fertility and worm survival in the rodents.

Onchocerca ochengi male worms implanted in SCID mice and Gerbil: Relationship between microfilaridermia status of cows, nodular worm viability and fertility and worm survival in the rodents.

Journal: Experimental parasitology
Published: July 26, 2020

Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis.

Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis.

Journal: The Journal of clinical investigation
Published: June 02, 2020

CXCR4 signaling controls dendritic cell location and activation at steady state and in inflammation.

CXCR4 signaling controls dendritic cell location and activation at steady state and in inflammation.

Journal: Blood
Published: April 29, 2020

Generation of Loa loa infective larvae by experimental infection of the vector, Chrysops silacea.

Generation of Loa loa infective larvae by experimental infection of the vector, Chrysops silacea.

Journal: PLoS neglected tropical diseases
Published: February 07, 2020

The insufficiency of circulating miRNA and DNA as diagnostic tools or as biomarkers of treatment efficacy for Onchocerca volvulus.

The insufficiency of circulating miRNA and DNA as diagnostic tools or as biomarkers of treatment efficacy for Onchocerca volvulus.

Journal: Scientific reports
Published: December 06, 2019

Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor Signaling.

Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor Signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950)
Published: October 15, 2019

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.

Journal: Science translational medicine
Published: October 13, 2018

Mouse models of Loa loa.

Mouse models of Loa loa.

Journal: Nature communications
Published: September 28, 2018

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.

Journal: Science translational medicine
Published: May 17, 2018
Showing 1-12 of 26

Last Updated: 09/26/2026