Nicolas Sireau
66 Devonshire Road
Cambridge, ENG, United Kingdom
Cambridge, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 14 publications
Identifying obstacles hindering the conduct of academic-sponsored trials for drug repurposing on rare-diseases: an analysis of six use cases.
Journal: Trials
Published: April 11, 2022
Clinical development innovation in rare diseases: lessons learned and best practices from the DevelopAKUre consortium.
Journal: Orphanet journal of rare diseases
Published: August 26, 2021
How to manage obsessive-compulsive disorder (OCD) under COVID-19: A clinician's guide from the International College of Obsessive Compulsive Spectrum Disorders (ICOCS) and the Obsessive-Compulsive and Related Disorders Research Network (OCRN) of the European College of Neuropsychopharmacology.
Journal: Comprehensive psychiatry
Published: April 02, 2020
Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial.
Journal: The lancet. Diabetes & endocrinology
Published: March 12, 2020
Alkaptonuria - Many questions answered, further challenges beckon.
Journal: Annals of clinical biochemistry
Published: September 19, 2019
A patient survey on the impact of alkaptonuria symptoms as perceived by the patients and their experiences of receiving diagnosis and care.
Journal: JIMD reports
Published: September 09, 2019
Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria.
Journal: Journal of inherited metabolic disease
Published: July 24, 2019
Data on items of AKUSSI in Alkaptonuria collected over three years from the United Kingdom National Alkaptonuria Centre and the impact of nitisinone.
Journal: Data in brief
Published: July 24, 2018
Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre.
Journal: Molecular genetics and metabolism
Published: March 28, 2018
Alkaptonuria: An example of a "fundamental disease"--A rare disease with important lessons for more common disorders.
Journal: Seminars in cell & developmental biology
Published: October 30, 2015
Old treatments for new insights and strategies: proposed management in adults and children with alkaptonuria.
Journal: Journal of inherited metabolic disease
Published: November 28, 2014
Last Updated: 09/26/2026