Nicole M. Duffy
Saint-laurent, QC H4S2A1, Canada
Last Updated: 09/26/2026
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Found 8 publications
Probing the Chemical Space of Polymerase Theta with Nucleotide Analogues Bearing a Stereogenic All-Carbon Quaternary Center.
Journal: ACS medicinal chemistry letters
Published: October 29, 2025
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
Journal: Journal of medicinal chemistry
Published: September 20, 2022
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
Journal: Journal of medicinal chemistry
Published: July 26, 2022
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
Journal: Nature
Published: April 20, 2021
A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: September 22, 2020
Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.
Journal: Molecular cell
Published: November 30, 2014
Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors.
Journal: Nature communications
Published: January 08, 2014
Showing 1-8 of 8
Last Updated: 09/26/2026