Nicole Stupka

176 Furlong Road
St Albans, VIC 3021, Australia

Last Updated: 09/26/2026

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Found 25 publications

Adamts5 deletion exacerbates inflammation and fibrosis resulting in compromised skeletal muscle regeneration.

Adamts5 deletion exacerbates inflammation and fibrosis resulting in compromised skeletal muscle regeneration.

Journal: American journal of physiology. Cell physiology

Published: January 28, 2026

ADAMTS-5 inhibition reduces muscle inflammation and fibrosis and improves function in mouse models of Duchenne muscular dystrophy.

ADAMTS-5 inhibition reduces muscle inflammation and fibrosis and improves function in mouse models of Duchenne muscular dystrophy.

Journal: Science translational medicine

Published: June 18, 2025

APE1/Ref-1 inhibition via APX3330 lowers monocyte/macrophage infiltration without ameliorating the structure and function of dystrophic mdx hindlimb muscles.

APE1/Ref-1 inhibition via APX3330 lowers monocyte/macrophage infiltration without ameliorating the structure and function of dystrophic mdx hindlimb muscles.

Journal: Physiological reports

Published: May 27, 2025

Repurposed Nrf2 activator dimethyl fumarate rescues muscle inflammation and fibrosis in an aggravated mdx mouse model of Duchenne muscular dystrophy.

Repurposed Nrf2 activator dimethyl fumarate rescues muscle inflammation and fibrosis in an aggravated mdx mouse model of Duchenne muscular dystrophy.

Journal: Redox biology

Published: March 18, 2025

The Potential of Targeting APE1/Ref-1 as a Therapeutic Intervention for Duchenne Muscular Dystrophy.

The Potential of Targeting APE1/Ref-1 as a Therapeutic Intervention for Duchenne Muscular Dystrophy.

Journal: Antioxidants & redox signaling

Published: December 27, 2024

In dystrophic mdx hindlimb muscles where fibrosis is limited, versican haploinsufficiency transiently improves contractile function without reducing inflammation.

In dystrophic mdx hindlimb muscles where fibrosis is limited, versican haploinsufficiency transiently improves contractile function without reducing inflammation.

Journal: American journal of physiology. Cell physiology

Published: August 19, 2024

Dimethyl fumarate modulates the dystrophic disease program following short-term treatment.

Dimethyl fumarate modulates the dystrophic disease program following short-term treatment.

Journal: JCI insight

Published: October 04, 2022

Targeting intramuscular adipose tissue expansion to preserve contractile function in volumetric muscle loss: A potentially novel therapy?

Targeting intramuscular adipose tissue expansion to preserve contractile function in volumetric muscle loss: A potentially novel therapy?

Journal: Current opinion in pharmacology

Published: January 07, 2021

Erratum: Treatment of Dystrophic mdx Mice with an ADAMTS-5 Specific Monoclonal Antibody Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles. Biomolecules 2020, 10, 416.

Erratum: Treatment of Dystrophic mdx Mice with an ADAMTS-5 Specific Monoclonal Antibody Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles. Biomolecules 2020, 10, 416.

Journal: Biomolecules

Published: July 09, 2020

1,25(OH)2D3 ameliorates palmitate-induced lipotoxicity in human primary osteoblasts leading to improved viability and function.

1,25(OH)2D3 ameliorates palmitate-induced lipotoxicity in human primary osteoblasts leading to improved viability and function.

Journal: Bone

Published: June 16, 2020

Pathogenesis of Osteoporosis.

Pathogenesis of Osteoporosis.

Journal: Handbook of experimental pharmacology

Published: April 17, 2020

Impaired exercise performance is independent of inflammation and cellular stress following genetic reduction or deletion of selenoprotein S.

Impaired exercise performance is independent of inflammation and cellular stress following genetic reduction or deletion of selenoprotein S.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology

Published: March 19, 2020

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Last Updated: 09/26/2026