Niels De Wind

Leiden, ZH 2333RC, Netherlands

Last Updated: 09/26/2026

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Found 46 publications

A common food mutagen promotes intestinal carcinogenesis by multiple mechanisms in mouse models of Lynch syndrome.

A common food mutagen promotes intestinal carcinogenesis by multiple mechanisms in mouse models of Lynch syndrome.

Journal: NAR cancer

Published: July 29, 2025

DNA mismatch repair controls the mutagenicity of Polymerase ζ-dependent translesion synthesis at methylated guanines.

DNA mismatch repair controls the mutagenicity of Polymerase ζ-dependent translesion synthesis at methylated guanines.

Journal: DNA repair

Published: May 05, 2024

Assessing pathogenicity of mismatch repair variants of uncertain significance by molecular tumor analysis.

Assessing pathogenicity of mismatch repair variants of uncertain significance by molecular tumor analysis.

Journal: Experimental and molecular pathology

Published: April 30, 2024

Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside.

Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside.

Journal: Heliyon

Published: January 12, 2023

Discordant Staining Patterns and Microsatellite Results in Tumors of MSH6 Pathogenic Variant Carriers.

Discordant Staining Patterns and Microsatellite Results in Tumors of MSH6 Pathogenic Variant Carriers.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Published: December 01, 2022

Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding.

Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding.

Journal: Nucleic acids research

Published: August 03, 2022

Rev1 deficiency induces replication stress to cause metabolic dysfunction differently in males and females.

Rev1 deficiency induces replication stress to cause metabolic dysfunction differently in males and females.

Journal: American journal of physiology. Endocrinology and metabolism

Published: February 14, 2022

CNOT6: A Novel Regulator of DNA Mismatch Repair.

CNOT6: A Novel Regulator of DNA Mismatch Repair.

Journal: Cells

Published: December 28, 2021

Predictive functional assay-based classification of PMS2 variants in Lynch syndrome.

Predictive functional assay-based classification of PMS2 variants in Lynch syndrome.

Journal: Human mutation

Published: November 09, 2021

Induction of mismatch repair deficiency, compromised DNA damage signaling and compound hypermutagenesis by a dietary mutagen in a cell-based model for Lynch syndrome.

Induction of mismatch repair deficiency, compromised DNA damage signaling and compound hypermutagenesis by a dietary mutagen in a cell-based model for Lynch syndrome.

Journal: Carcinogenesis

Published: July 05, 2021

DNA mismatch repair-dependent DNA damage responses and cancer.

DNA mismatch repair-dependent DNA damage responses and cancer.

Journal: DNA repair

Published: October 22, 2020

Digenic inheritance of MSH6 and MUTYH variants in familial colorectal cancer.

Digenic inheritance of MSH6 and MUTYH variants in familial colorectal cancer.

Journal: Genes, chromosomes & cancer

Published: March 04, 2020

Showing 1-12 of 46

Last Updated: 09/26/2026