Nigel J. Pyne

Glasgow, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 67 publications

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes.

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes.

Journal: British journal of pharmacology
Published: December 29, 2025

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes.

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes.

Journal: British journal of pharmacology
Published: December 20, 2023

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes.

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes.

Journal: British journal of pharmacology
Published: September 16, 2021

Dihydroceramide Desaturase Functions as an Inducer and Rectifier of Apoptosis: Effect of Retinol Derivatives, Antioxidants and Phenolic Compounds.

Dihydroceramide Desaturase Functions as an Inducer and Rectifier of Apoptosis: Effect of Retinol Derivatives, Antioxidants and Phenolic Compounds.

Journal: Cell biochemistry and biophysics
Published: February 23, 2021

A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells.

A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells.

Journal: The Journal of biological chemistry
Published: February 08, 2021

A Novel Selective Sphingosine Kinase 2 Inhibitor, HWG-35D, Ameliorates the Severity of Imiquimod-Induced Psoriasis Model by Blocking Th17 Differentiation of Naïve CD4 T Lymphocytes.

A Novel Selective Sphingosine Kinase 2 Inhibitor, HWG-35D, Ameliorates the Severity of Imiquimod-Induced Psoriasis Model by Blocking Th17 Differentiation of Naïve CD4 T Lymphocytes.

Journal: International journal of molecular sciences
Published: October 22, 2020

Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis.

Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis.

Journal: Cellular signalling
Published: September 28, 2020

Structure-function analysis of lipid substrates and inhibitors of sphingosine kinases.

Structure-function analysis of lipid substrates and inhibitors of sphingosine kinases.

Journal: Cellular signalling
Published: September 08, 2020

Recent advances in the role of sphingosine 1-phosphate in cancer.

Recent advances in the role of sphingosine 1-phosphate in cancer.

Journal: FEBS letters
Published: August 22, 2020

Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.

Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.

Journal: Nature communications
Published: April 22, 2020

Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1.

Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1.

Journal: Cells
Published: March 20, 2020

Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.

Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 19, 2019
Showing 1-12 of 67

Last Updated: 09/26/2026