Nikhil S. Gadewal

Navi Mumbai, MH, India

Last Updated: 09/26/2026

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Found 40 publications

Hotspot mutations in HER2 interfaces destabilize structure, causing breast cancer treatment failure.

Hotspot mutations in HER2 interfaces destabilize structure, causing breast cancer treatment failure.

Journal: Research square

Published: April 01, 2025

Hotspot mutations in HER2 interfaces destabilize structure, causing breast cancer treatment failure.

Hotspot mutations in HER2 interfaces destabilize structure, causing breast cancer treatment failure.

Journal: Oncogene

Published: January 30, 2025

The deubiquitinase inhibitor WP1130 drives nuclear aggregation and reactivation of mutant p53 for selective cancer cell targeting.

The deubiquitinase inhibitor WP1130 drives nuclear aggregation and reactivation of mutant p53 for selective cancer cell targeting.

Journal: The FEBS journal

Published: November 15, 2024

In silico screening of phytochemicals against chromatin modifier, SETD7 for remodeling of the immunosuppressive tumor microenvironment in renal cancer.

In silico screening of phytochemicals against chromatin modifier, SETD7 for remodeling of the immunosuppressive tumor microenvironment in renal cancer.

Journal: Molecular diversity

Published: June 04, 2024

Mechanistic influence of discreet conformation of human telomerase linker region.

Mechanistic influence of discreet conformation of human telomerase linker region.

Journal: Journal of biomolecular structure & dynamics

Published: February 06, 2024

High-throughput sequencing and in-silico analysis confirm pathogenicity of novel MSH3 variants in African American colorectal cancer.

High-throughput sequencing and in-silico analysis confirm pathogenicity of novel MSH3 variants in African American colorectal cancer.

Journal: Neoplasia (New York, N.Y.)

Published: November 05, 2023

Integrative epigenome-transcriptome analysis unravels cancer-specific over-expressed genes potentially regulating immune microenvironment in clear cell renal cell carcinoma.

Integrative epigenome-transcriptome analysis unravels cancer-specific over-expressed genes potentially regulating immune microenvironment in clear cell renal cell carcinoma.

Journal: Biochimica et biophysica acta. General subjects

Published: June 16, 2023

Pathogenic HER3 dimerization domain mutations create a structural bias towards un-conventional EGFR-HER3 signalling axis in breast cancer.

Pathogenic HER3 dimerization domain mutations create a structural bias towards un-conventional EGFR-HER3 signalling axis in breast cancer.

Journal: International journal of biological macromolecules

Published: November 08, 2022

Loss of correlated proteasomal subunit expression selectively promotes the 20SHigh state which underlies luminal breast tumorigenicity.

Loss of correlated proteasomal subunit expression selectively promotes the 20SHigh state which underlies luminal breast tumorigenicity.

Journal: Communications biology

Published: April 08, 2022

ARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications.

ARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications.

Journal: Cancer gene therapy

Published: February 11, 2022

Molecular docking analysis of hyperphosphorylated tau protein with compounds derived from Bacopa monnieri and Withania somnifera.

Molecular docking analysis of hyperphosphorylated tau protein with compounds derived from Bacopa monnieri and Withania somnifera.

Journal: Bioinformation

Published: August 16, 2021

Downregulation of ARID1B, a tumor suppressor in the WNT subgroup medulloblastoma, activates multiple oncogenic signaling pathways.

Downregulation of ARID1B, a tumor suppressor in the WNT subgroup medulloblastoma, activates multiple oncogenic signaling pathways.

Journal: Human molecular genetics

Published: April 02, 2021

Showing 1-12 of 40

Last Updated: 09/26/2026