Niklas P. Larsson

AstraZeneca R&D
Moelndal, O 43150, Sweden

Last Updated: 09/26/2026

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Found 25 publications

Discovery of AZD4144, a Selective and Potent NLRP3 Inhibitor for the Treatment of Inflammatory Diseases.

Discovery of AZD4144, a Selective and Potent NLRP3 Inhibitor for the Treatment of Inflammatory Diseases.

Journal: Journal of medicinal chemistry

Published: July 09, 2025

Inhibition of soluble epoxide hydrolase in endotoxin induced pig lung injury.

Inhibition of soluble epoxide hydrolase in endotoxin induced pig lung injury.

Journal: Frontiers in pharmacology

Published: June 23, 2025

Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model.

Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model.

Journal: PloS one

Published: October 30, 2024

A novel long-acting relaxin-2 fusion, AZD3427, improves cardiac performance in non-human primates with cardiac dysfunction.

A novel long-acting relaxin-2 fusion, AZD3427, improves cardiac performance in non-human primates with cardiac dysfunction.

Journal: Cardiovascular research

Published: August 17, 2024

Identification of Novel Series of Potent and Selective Relaxin Family Peptide Receptor 1 (RXFP1) Agonists.

Identification of Novel Series of Potent and Selective Relaxin Family Peptide Receptor 1 (RXFP1) Agonists.

Journal: Journal of medicinal chemistry

Published: March 19, 2024

Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure.

Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure.

Journal: Journal of medicinal chemistry

Published: March 19, 2024

Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.

Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.

Journal: Nutrients

Published: July 14, 2023

Oxylipin Profiles during the First Day of Mechanical Ventilation in an Intensive Care Unit Cohort: Research Letter.

Oxylipin Profiles during the First Day of Mechanical Ventilation in an Intensive Care Unit Cohort: Research Letter.

Journal: Anesthesiology

Published: March 01, 2023

Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists.

Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists.

Journal: Journal of medicinal chemistry

Published: September 27, 2022

Plasma and bronchoalveolar lavage fluid oxylipin levels in experimental porcine lung injury.

Plasma and bronchoalveolar lavage fluid oxylipin levels in experimental porcine lung injury.

Journal: Prostaglandins & other lipid mediators

Published: October 06, 2021

Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework.

Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework.

Journal: Journal of medicinal chemistry

Published: July 01, 2021

New Lactiplantibacillus plantarum and Lacticaseibacillus rhamnosus strains: well tolerated and improve infant microbiota.

New Lactiplantibacillus plantarum and Lacticaseibacillus rhamnosus strains: well tolerated and improve infant microbiota.

Journal: Pediatric research

Published: December 23, 2020

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Last Updated: 09/26/2026