Nils Billestrup

Copenhagen, Denmark

Last Updated: 09/26/2026

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Found 28 publications

Protection of beta cells against cytokine-induced apoptosis by the gut microbial metabolite butyrate.

Protection of beta cells against cytokine-induced apoptosis by the gut microbial metabolite butyrate.

Journal: The FEBS journal
Published: July 04, 2024

Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction.

Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction.

Journal: The FEBS journal
Published: July 31, 2023

Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice.

Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice.

Journal: International journal of molecular sciences
Published: January 30, 2023

Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.

Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.

Journal: Cell death & disease
Published: November 11, 2022

Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells.

Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells.

Journal: The Journal of biological chemistry
Published: February 21, 2022

Butyrate Protects Pancreatic Beta Cells from Cytokine-Induced Dysfunction.

Butyrate Protects Pancreatic Beta Cells from Cytokine-Induced Dysfunction.

Journal: International journal of molecular sciences
Published: September 08, 2021

Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.

Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.

Journal: Molecular and cellular endocrinology
Published: February 19, 2019

In-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes.

In-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes.

Journal: European journal of pharmacology
Published: August 28, 2017

Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics).

Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics).

Journal: Molecular & cellular proteomics : MCP
Published: July 27, 2017

Pannexin-2-deficiency sensitizes pancreatic β-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo.

Pannexin-2-deficiency sensitizes pancreatic β-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo.

Journal: Molecular and cellular endocrinology
Published: November 29, 2016

Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro.

Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro.

Journal: Endocrinology
Published: August 02, 2016

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity.

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity.

Journal: Diabetes
Published: February 05, 2016
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Last Updated: 09/26/2026