Noah Isakov
Beersheba, D, Israel
Last Updated: 09/26/2026
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Found 35 publications
Uttroside B, a US FDA-designated 'Orphan Drug', mitigates the development of hepatocellular carcinoma and its pulmonary metastasis via EGFR/ERK-mediated inhibition of SREBP-1 and STAT-3.
Journal: Cell death discovery
Published: August 05, 2025
The peptidyl-prolyl cis-trans isomerase, Pin1, is a regulator of the protein kinase C θ (PKCθ) catalytic activity in activated T cells.
Journal: Protein science : a publication of the Protein Society
Published: May 14, 2025
Orphan drug uttroside B impedes MASH progression and HCC development in experimental models.
Journal: JHEP reports : innovation in hepatology
Published: December 19, 2024
Mechanisms of Cbl-Mediated Ubiquitination of Proteins in T and Natural Killer Cells and Effects on Immune Cell Functions.
Journal: Life (Basel, Switzerland)
Published: October 04, 2024
The Peptidyl-Prolyl cis-trans isomerase, Pin1, associates with Protein Kinase C θ via a critical Phospho-Thr-Pro motif in the V3 regulatory domain.
Journal: Frontiers in immunology
Published: December 17, 2022
The role of AMPK in cancer metabolism and its impact on the immunomodulation of the tumor microenvironment.
Journal: Frontiers in immunology
Published: December 02, 2022
Termination of TCR-mediated activation signals is regulated by CrkII-dependent Cbl-mediated ubiquitination and degradation of C3G.
Journal: Immunobiology
Published: October 30, 2022
Decoupling the role of RORγt in the differentiation and effector function of TH17 cells.
Journal: Science advances
Published: October 21, 2022
Corrigendum: Blockade of uttroside B-induced autophagic pro-survival signals augments its chemotherapeutic efficacy against hepatocellular carcinoma.
Journal: Frontiers in oncology
Published: July 11, 2022
Cyclophilin A associates with and regulates the activity of ZAP70 in TCR/CD3-stimulated T cells.
Journal: Cellular and molecular life sciences : CMLS
Published: June 22, 2022
Steroid nuclear receptor coactivator 2 controls immune tolerance by promoting induced Treg differentiation via up-regulating Nr4a2.
Journal: Science advances
Published: June 15, 2022
Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: March 27, 2022
Last Updated: 09/26/2026