Nobuhiko Hiraga

Hiroshima, Japan

Last Updated: 09/26/2026

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Found 58 publications

Interferon alpha induces a stronger antiviral effect than interferon lambda in HBV/HDV infected humanized mice.

Interferon alpha induces a stronger antiviral effect than interferon lambda in HBV/HDV infected humanized mice.

Journal: Virus research

Published: May 21, 2024

Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics.

Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics.

Journal: PLoS computational biology

Published: November 02, 2022

Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.

Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.

Journal: Journal of gastroenterology

Published: July 09, 2018

Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes.

Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes.

Journal: Virology

Published: July 09, 2018

Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure.

Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure.

Journal: The Journal of general virology

Published: June 20, 2018

CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients.

CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients.

Journal: Journal of viral hepatitis

Published: March 30, 2018

Acute hepatitis B virus infection in humanized chimeric mice has multiphasic viral kinetics.

Acute hepatitis B virus infection in humanized chimeric mice has multiphasic viral kinetics.

Journal: Hepatology (Baltimore, Md.)

Published: August 04, 2017

Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice.

Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice.

Journal: Antimicrobial agents and chemotherapy

Published: April 10, 2017

Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease.

Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease.

Journal: Journal of gastroenterology

Published: March 30, 2017

Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology.

Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology.

Journal: The Journal of general virology

Published: February 01, 2017

Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus.

Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus.

Journal: Antimicrobial agents and chemotherapy

Published: January 30, 2017

Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus.

Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus.

Journal: PloS one

Published: September 28, 2016

Showing 1-12 of 58

Last Updated: 09/26/2026