Nobutaka Hirokawa

Tokyo, 1138421, Japan

Last Updated: 09/26/2026

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Found 67 publications

The hook-like adaptor and cargo-binding (HAC) domain in the kinesin-2 tail enables adaptor assembly and cargo recognition.

The hook-like adaptor and cargo-binding (HAC) domain in the kinesin-2 tail enables adaptor assembly and cargo recognition.

Journal: Science advances
Published: October 24, 2025

The KIF3B/B/KAP3 tail domain specifically facilitates TRIM46 transport to the axon initial segment.

The KIF3B/B/KAP3 tail domain specifically facilitates TRIM46 transport to the axon initial segment.

Journal: The Journal of cell biology
Published: March 26, 2025

Mutations in the kinesin KIF12 promote MASH in humans and mice by disrupting lipogenic enzyme turnover.

Mutations in the kinesin KIF12 promote MASH in humans and mice by disrupting lipogenic enzyme turnover.

Journal: The EMBO journal
Published: May 14, 2024

Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis.

Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis.

Journal: EMBO reports
Published: December 20, 2023

A novel in-frame deletion in KIF5C gene causes infantile onset epilepsy and psychomotor retardation.

A novel in-frame deletion in KIF5C gene causes infantile onset epilepsy and psychomotor retardation.

Journal: MedComm
Published: May 26, 2023

The two-step cargo recognition mechanism of heterotrimeric kinesin.

The two-step cargo recognition mechanism of heterotrimeric kinesin.

Journal: EMBO reports
Published: January 23, 2023

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

Journal: The Journal of cell biology
Published: August 19, 2022

KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.

KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.

Journal: Developmental cell
Published: March 05, 2022

Nodal flow transfers polycystin to determine mouse left-right asymmetry.

Nodal flow transfers polycystin to determine mouse left-right asymmetry.

Journal: Developmental cell
Published: October 27, 2021

A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle.

A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle.

Journal: The EMBO journal
Published: June 07, 2021

Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport.

Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport.

Journal: Cell reports
Published: May 21, 2020

An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility.

An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility.

Journal: Science advances
Published: May 16, 2020
Showing 1-12 of 67

Last Updated: 09/26/2026