Nobuyuki Amano
Fujisawa, Japan
Last Updated: 09/26/2026
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Found 35 publications
SLC52A1 is a neofunctionalized primate urate transporter enabling intestinal urate secretion.
Journal: The Journal of biological chemistry
Published: November 22, 2025
Preclinical characterization of pharmacokinetics, enzyme occupancy, and pharmacodynamics of soticlestat (TAK-935), a novel cholesterol 24-hydroxylase inhibitor.
Journal: The Journal of pharmacology and experimental therapeutics
Published: September 30, 2025
Involvement of Proton-Coupled Organic Cation Antiporter in Human Blood-Brain Barrier Transport of Mesoridazine and Metoclopramide.
Journal: Biological & pharmaceutical bulletin
Published: October 16, 2024
Correction to: Construction and Functional Evaluation of a Three-Dimensional Blood-Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells.
Journal: Pharmaceutical research
Published: April 20, 2022
Construction and Functional Evaluation of a Three-Dimensional Blood-Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells.
Journal: Pharmaceutical research
Published: November 29, 2021
Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: August 12, 2020
Microminipig: A suitable animal model to estimate oral absorption of sustained-release formulation in humans.
Journal: International journal of pharmaceutics
Published: January 07, 2020
Utility of hairless rats as a model for predicting transdermal pharmacokinetics in humans.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: December 10, 2019
Discovery of 1,8-naphthyridin-2-one derivative as a potent and selective sphingomyelin synthase 2 inhibitor.
Journal: Bioorganic & medicinal chemistry
Published: December 03, 2019
Relationship of MATE1 Inhibition and Cytotoxicity in Nephrotoxicity: Application for Safety Evaluation in Early Drug Discovery.
Journal: Toxicological sciences : an official journal of the Society of Toxicology
Published: April 26, 2019
Prediction of human pharmacokinetics of long half-life compounds using chimeric mice with humanised liver.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: February 13, 2019
Application of unbound liver-to-plasma concentration ratio to quantitative projection of cytochrome P450-mediated drug-drug interactions using physiologically based pharmacokinetic modelling approach.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: December 06, 2018
Last Updated: 09/26/2026