Nora Rauch

Dublin, L, Ireland

Last Updated: 09/26/2026

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Found 18 publications

Dual RAF inhibition outperforms RAF-MEK combinations for suppressing ERK signaling in KRAS mutant cells.

Dual RAF inhibition outperforms RAF-MEK combinations for suppressing ERK signaling in KRAS mutant cells.

Journal: NPJ systems biology and applications
Published: July 29, 2025

Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells.

Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells.

Journal: Cell reports
Published: December 19, 2023

Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells.

Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells.

Journal: International journal of molecular sciences
Published: June 30, 2023

A Combination of Conformation-Specific RAF Inhibitors Overcome Drug Resistance Brought about by RAF Overexpression.

A Combination of Conformation-Specific RAF Inhibitors Overcome Drug Resistance Brought about by RAF Overexpression.

Journal: Biomolecules
Published: May 22, 2023

Interactome dynamics of RAF1-BRAF kinase monomers and dimers.

Interactome dynamics of RAF1-BRAF kinase monomers and dimers.

Journal: Scientific data
Published: September 21, 2022

Control of cell state transitions.

Control of cell state transitions.

Journal: Nature
Published: January 11, 2021

A systematic analysis of signaling reactivation and drug resistance.

A systematic analysis of signaling reactivation and drug resistance.

Journal: Cell reports
Published: August 27, 2020

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D.

Journal: Nature communications
Published: May 11, 2019

Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling.

Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling.

Journal: Cell systems
Published: October 06, 2017

PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359.

PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359.

Journal: Cell reports
Published: September 04, 2017

Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization.

Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization.

Journal: EMBO reports
Published: May 23, 2017

A novel RNA sequencing data analysis method for cell line authentication.

A novel RNA sequencing data analysis method for cell line authentication.

Journal: PloS one
Published: September 01, 2016
Showing 1-12 of 18

Last Updated: 09/26/2026