Norbert Wiedemann
Lausanne, VD, Switzerland
Last Updated: 09/26/2026
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Found 9 publications
Preclinical Characterization of DPI-4452: A 68Ga/177Lu Theranostic Ligand for Carbonic Anhydrase IX.
Preclinical Characterization of DPI-4452: A 68Ga/177Lu Theranostic Ligand for Carbonic Anhydrase IX.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Published: July 27, 2023
Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models.
Journal: Cell death & disease
Published: November 09, 2020
The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice.
Journal: PloS one
Published: September 04, 2019
DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death.
Journal: Scientific reports
Published: August 01, 2018
SMAC Mimetic Debio 1143 and Ablative Radiation Therapy Synergize to Enhance Antitumor Immunity against Lung Cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: January 19, 2018
SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.
Journal: Oncotarget
Published: September 25, 2015
BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.
Journal: EBioMedicine
Published: August 24, 2015
The radiosensitizing activity of the SMAC-mimetic, Debio 1143, is TNFα-mediated in head and neck squamous cell carcinoma.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published: April 21, 2015
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Last Updated: 09/26/2026