Olav M. Andersen

Arhus, Denmark

Last Updated: 09/26/2026

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Found 40 publications

SORL1 variant links endosomal amyloid precursor protein mis-sorting to axonal transport defects and neuronal dysfunction.

SORL1 variant links endosomal amyloid precursor protein mis-sorting to axonal transport defects and neuronal dysfunction.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: January 15, 2026

SorLA regulates B cell receptor uptake, trafficking, and B cell-mediated immune responses in vivo.

SorLA regulates B cell receptor uptake, trafficking, and B cell-mediated immune responses in vivo.

Journal: The Journal of experimental medicine

Published: November 12, 2025

A luminescent reporter assay to quantify SORL1 ectodomain shedding and retromer-dependent endosome recycling activity.

A luminescent reporter assay to quantify SORL1 ectodomain shedding and retromer-dependent endosome recycling activity.

Journal: The Journal of biological chemistry

Published: October 02, 2025

Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants.

Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: September 12, 2025

Familial Alzheimer's disease mutation identifies novel role of SORLA in release of neurotrophic exosomes.

Familial Alzheimer's disease mutation identifies novel role of SORLA in release of neurotrophic exosomes.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: April 11, 2025

Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer's disease.

Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer's disease.

Journal: Molecular neurodegeneration

Published: February 20, 2025

Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity.

Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity.

Journal: Nature communications

Published: September 20, 2024

The SORL1 p.Y1816C variant causes impaired endosomal dimerization and autosomal dominant Alzheimer's disease.

The SORL1 p.Y1816C variant causes impaired endosomal dimerization and autosomal dominant Alzheimer's disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 03, 2024

Functional characterization of SORL1 variants in cell-based assays to investigate variant pathogenicity.

Functional characterization of SORL1 variants in cell-based assays to investigate variant pathogenicity.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Published: February 18, 2024

Mice and minipigs with compromised expression of the Alzheimer's disease gene SORL1 show cerebral metabolic disturbances on hyperpolarized [1-13C]pyruvate and sodium MRI.

Mice and minipigs with compromised expression of the Alzheimer's disease gene SORL1 show cerebral metabolic disturbances on hyperpolarized [1-13C]pyruvate and sodium MRI.

Journal: Brain communications

Published: November 30, 2023

On the causal role of retromer-dependent endosomal recycling in Alzheimer's disease.

On the causal role of retromer-dependent endosomal recycling in Alzheimer's disease.

Journal: Nature cell biology

Published: October 06, 2023

SorLA restricts TNFα release from microglia to shape a glioma-supportive brain microenvironment.

SorLA restricts TNFα release from microglia to shape a glioma-supportive brain microenvironment.

Journal: EMBO reports

Published: August 30, 2023

Showing 1-12 of 40

Last Updated: 09/26/2026