Olga Svecova
Brno, JM 62500, Czech Republic
Last Updated: 09/26/2026
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Found 15 publications
C-terminal long-QT type 1 R562S-Kv7.1 variant, the first variant in helix C impairing β-adrenergic response of the slow delayed rectifier K+ channel.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Published: April 07, 2026
C-terminal long-QT type 1 R562S-Kv7.1 variant, the first variant in helix C impairing β-adrenergic response of the slow delayed rectifier K+ channel.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Published: April 07, 2026
Patient-Derived PSEN1 Cerebral Organoids Revealed Parallel Development of Amyloid-β Accumulation and Network Dysfunction.
Journal: Cellular and molecular neurobiology
Published: December 16, 2025
Identification and functional assessment of a KCNH2 compound heterozygosity in a patient with presumed idiopathic ventricular fibrillation ascertains the diagnosis of long QT syndrome type 2.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Published: November 06, 2025
Field potential duration and its variability as essential parameters for revealing proarrhythmia: problematic aspects of analysis in cardiomyocytes derived from human pluripotent stem cells.
Journal: Progress in biophysics and molecular biology
Published: October 06, 2025
Aminophylline at clinically relevant concentrations affects inward rectifier potassium current in healthy porcine and failing human cardiomyocytes in a similar manner.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: November 01, 2024
Sildenafil affects the human Kir2.1 and Kir2.2 channels at clinically relevant concentrations: Inhibition potentiated by low Ba2.
Journal: Frontiers in pharmacology
Published: January 02, 2023
A new approach to the determination of tubular membrane capacitance: passive membrane electrical properties under reduced electrical conductivity of the extracellular solution.
Journal: Pflugers Archiv : European journal of physiology
Published: July 28, 2022
Fraction of the T-Tubular Membrane as an Important Parameter in Cardiac Cellular Electrophysiology: A New Way of Estimation.
Journal: Frontiers in physiology
Published: December 16, 2021
Combination of Sildenafil and Ba2+ at a Low Concentration Show a Significant Synergistic Inhibition of Inward Rectifier Potassium Current Resulting in Action Potential Prolongation.
Journal: Frontiers in pharmacology
Published: December 06, 2021
Aminophylline at clinically relevant concentrations affects inward rectifier potassium current in a dual way.
Journal: Pflugers Archiv : European journal of physiology
Published: July 22, 2021
Author Correction: Long-QT founder variant T309I-Kv7.1 with dominant negative pattern may predispose delayed afterdepolarizations under β-adrenergic stimulation.
Journal: Scientific reports
Published: April 30, 2021
Last Updated: 09/26/2026